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- W2270798032 abstract "CASR gene appears to be involved in cancer biology and physiology. However, a number of studies investigating CASR polymorphisms and cancer risks have presented inconclusive results. Thus, a systematic review and a meta-analysis of the effect of CASR polymorphisms on several cancer risks were performed to suggest a statistical evidence for the association of CASR polymorphisms with cancer risks.MEDLINE, EMBASE, Web of Science, Scopus, and the HuGE databases were searched. Nineteen articles of case-control and cohort studies were included for the final analysis.The colorectal cancer risk was reduced in proximal (odds ratio [OR] =0.679, P=0.001) and distal (OR =0.753, P=0.026) colon sites with GG genotype of CASR rs1042636 and increased in distal colon site (OR =1.418, P=0.039) with GG genotype of rs1801726 by additive genetic model. The rs17251221 demonstrated noticeable associations that carrying a homozygote variant increases breast and prostate cancer risk considerably.The significant association of CASR polymorphisms with several cancer risks was observed in this review. In particular, the act of CASR polymorphisms as a tumor suppressor or an oncogene differs by cancer site and can be the research target for tumorigenesis." @default.
- W2270798032 created "2016-06-24" @default.
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- W2270798032 date "2016-02-01" @default.
- W2270798032 modified "2023-10-14" @default.
- W2270798032 title "Genetic polymorphisms of CASR and cancer risk: evidence from meta-analysis and HuGE review" @default.
- W2270798032 cites W1963580328 @default.
- W2270798032 cites W1969986140 @default.
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- W2270798032 cites W1972964586 @default.
- W2270798032 cites W1975106201 @default.
- W2270798032 cites W1982915376 @default.
- W2270798032 cites W1984713132 @default.
- W2270798032 cites W1986539195 @default.
- W2270798032 cites W1986702099 @default.
- W2270798032 cites W1988400664 @default.
- W2270798032 cites W1990058505 @default.
- W2270798032 cites W1998358624 @default.
- W2270798032 cites W2000435171 @default.
- W2270798032 cites W2008603620 @default.
- W2270798032 cites W2009441758 @default.
- W2270798032 cites W2012919091 @default.
- W2270798032 cites W2023153884 @default.
- W2270798032 cites W2028180556 @default.
- W2270798032 cites W2028547764 @default.
- W2270798032 cites W2032580335 @default.
- W2270798032 cites W2038809664 @default.
- W2270798032 cites W2039418122 @default.
- W2270798032 cites W2040217637 @default.
- W2270798032 cites W2041380953 @default.
- W2270798032 cites W2043673831 @default.
- W2270798032 cites W2059538482 @default.
- W2270798032 cites W2060117414 @default.
- W2270798032 cites W2064325095 @default.
- W2270798032 cites W2065195395 @default.
- W2270798032 cites W2072723883 @default.
- W2270798032 cites W2073094322 @default.
- W2270798032 cites W2075929294 @default.
- W2270798032 cites W2077470777 @default.
- W2270798032 cites W2077965603 @default.
- W2270798032 cites W2079205153 @default.
- W2270798032 cites W2079212189 @default.
- W2270798032 cites W2084954009 @default.
- W2270798032 cites W2094064127 @default.
- W2270798032 cites W2095462083 @default.
- W2270798032 cites W2096517063 @default.
- W2270798032 cites W2101463340 @default.
- W2270798032 cites W2102969047 @default.
- W2270798032 cites W2103601316 @default.
- W2270798032 cites W2107100887 @default.
- W2270798032 cites W2117788878 @default.
- W2270798032 cites W2119605658 @default.
- W2270798032 cites W2122047019 @default.
- W2270798032 cites W2128201302 @default.
- W2270798032 cites W2128517815 @default.
- W2270798032 cites W2132646585 @default.
- W2270798032 cites W2137993909 @default.
- W2270798032 cites W2138733161 @default.
- W2270798032 cites W2139745438 @default.
- W2270798032 cites W2142155920 @default.
- W2270798032 cites W2143238378 @default.
- W2270798032 cites W2145194362 @default.
- W2270798032 cites W2150639379 @default.
- W2270798032 cites W2150910286 @default.
- W2270798032 cites W2152879728 @default.
- W2270798032 cites W2155360150 @default.
- W2270798032 cites W2156835178 @default.
- W2270798032 cites W2157740198 @default.
- W2270798032 cites W2157823046 @default.
- W2270798032 cites W2160658964 @default.
- W2270798032 cites W2160710777 @default.
- W2270798032 cites W2160938004 @default.
- W2270798032 cites W2163577786 @default.
- W2270798032 cites W2165970663 @default.
- W2270798032 cites W2167233279 @default.
- W2270798032 cites W2170949021 @default.
- W2270798032 cites W2171151551 @default.
- W2270798032 cites W2186212929 @default.
- W2270798032 cites W2238434440 @default.
- W2270798032 cites W2417898164 @default.
- W2270798032 cites W2460069449 @default.
- W2270798032 cites W2467824185 @default.
- W2270798032 cites W39424341 @default.
- W2270798032 doi "https://doi.org/10.2147/ott.s97602" @default.
- W2270798032 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4755434" @default.
- W2270798032 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26929638" @default.
- W2270798032 hasPublicationYear "2016" @default.
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