Matches in SemOpenAlex for { <https://semopenalex.org/work/W2270924596> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2270924596 abstract "Phosphagen kinases aid in cellular regulation of energy homeostasis through the transfer of high-energy phosphates to acceptor compounds such as creatine or arginine for later use when energy demands are high. Two significant subfamilies of PKs include arginine kinases and creatine kinases. The physiological roles of the CK family have been extensively studied, but less is known about the physiological roles of AKs. C. elegans is a well-developed model system that can be used to develop our understanding of the evolution of the physiological roles of AKs. In this study, the activities of four separate AK isomers, isolated from C. elegans, were characterized and found to be similar to other AKs, validating the use of this model system. We are now attempting to determine if the localization pattern of these AKs is similar to what has been observed in CKs. One C. elegans AK isoform was identified as being potentially mitochondrially localized on the basis of putative signal sequences observed at the N-terminus. Preliminary immunohistochemistry results indicate that this isoform is restricted in tissue expression to muscle and possibly nervous tissue, indicating that tissue restricted expression of isoforms in this family evolved early. Our current efforts are directed at determining if it is resident in the mitochondria." @default.
- W2270924596 created "2016-06-24" @default.
- W2270924596 creator A5000679063 @default.
- W2270924596 creator A5004884431 @default.
- W2270924596 creator A5040374922 @default.
- W2270924596 creator A5063616345 @default.
- W2270924596 creator A5066402048 @default.
- W2270924596 date "2008-03-01" @default.
- W2270924596 modified "2023-10-05" @default.
- W2270924596 title "Characterization of the arginine kinase family of Caenorhabditis elegans" @default.
- W2270924596 doi "https://doi.org/10.1096/fasebj.22.1_supplement.1004.4" @default.
- W2270924596 hasPublicationYear "2008" @default.
- W2270924596 type Work @default.
- W2270924596 sameAs 2270924596 @default.
- W2270924596 citedByCount "1" @default.
- W2270924596 crossrefType "journal-article" @default.
- W2270924596 hasAuthorship W2270924596A5000679063 @default.
- W2270924596 hasAuthorship W2270924596A5004884431 @default.
- W2270924596 hasAuthorship W2270924596A5040374922 @default.
- W2270924596 hasAuthorship W2270924596A5063616345 @default.
- W2270924596 hasAuthorship W2270924596A5066402048 @default.
- W2270924596 hasConcept C104317684 @default.
- W2270924596 hasConcept C170493617 @default.
- W2270924596 hasConcept C184235292 @default.
- W2270924596 hasConcept C2491326 @default.
- W2270924596 hasConcept C2776277561 @default.
- W2270924596 hasConcept C2777468819 @default.
- W2270924596 hasConcept C2778944004 @default.
- W2270924596 hasConcept C28859421 @default.
- W2270924596 hasConcept C36880943 @default.
- W2270924596 hasConcept C515207424 @default.
- W2270924596 hasConcept C53345823 @default.
- W2270924596 hasConcept C55493867 @default.
- W2270924596 hasConcept C63645605 @default.
- W2270924596 hasConcept C86803240 @default.
- W2270924596 hasConcept C95444343 @default.
- W2270924596 hasConceptScore W2270924596C104317684 @default.
- W2270924596 hasConceptScore W2270924596C170493617 @default.
- W2270924596 hasConceptScore W2270924596C184235292 @default.
- W2270924596 hasConceptScore W2270924596C2491326 @default.
- W2270924596 hasConceptScore W2270924596C2776277561 @default.
- W2270924596 hasConceptScore W2270924596C2777468819 @default.
- W2270924596 hasConceptScore W2270924596C2778944004 @default.
- W2270924596 hasConceptScore W2270924596C28859421 @default.
- W2270924596 hasConceptScore W2270924596C36880943 @default.
- W2270924596 hasConceptScore W2270924596C515207424 @default.
- W2270924596 hasConceptScore W2270924596C53345823 @default.
- W2270924596 hasConceptScore W2270924596C55493867 @default.
- W2270924596 hasConceptScore W2270924596C63645605 @default.
- W2270924596 hasConceptScore W2270924596C86803240 @default.
- W2270924596 hasConceptScore W2270924596C95444343 @default.
- W2270924596 hasIssue "S1" @default.
- W2270924596 hasLocation W22709245961 @default.
- W2270924596 hasOpenAccess W2270924596 @default.
- W2270924596 hasPrimaryLocation W22709245961 @default.
- W2270924596 hasRelatedWork W1485893555 @default.
- W2270924596 hasRelatedWork W1542085789 @default.
- W2270924596 hasRelatedWork W2010575034 @default.
- W2270924596 hasRelatedWork W2015655561 @default.
- W2270924596 hasRelatedWork W2027555038 @default.
- W2270924596 hasRelatedWork W2030891043 @default.
- W2270924596 hasRelatedWork W2043407433 @default.
- W2270924596 hasRelatedWork W2402888260 @default.
- W2270924596 hasRelatedWork W901832989 @default.
- W2270924596 hasRelatedWork W2018949027 @default.
- W2270924596 hasVolume "22" @default.
- W2270924596 isParatext "false" @default.
- W2270924596 isRetracted "false" @default.
- W2270924596 magId "2270924596" @default.
- W2270924596 workType "article" @default.