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• W2271525555 abstract "Abstract Granulocyte colony-stimulating factor (G-CSF) in the cerebrospinal fluid from patients with meningitis was measured by our modified enzyme- linked immunosorbent assay for G-CSF. The minimal detection level was 20 pg/mL G-CSF. In patients with bacterial meningitis, the G-CSF levels in the cerebrospinal fluid were extremely elevated, showing a mean value of approximately 1,500 pg/mL. On the other hand, G-CSF levels in the cerebrospinal fluid from 67% patients with aseptic meningitis were moderately increased, showing a mean value of about 80 pg/mL, whereas G- CSF levels in 33% samples remained undetectable. The G-CSF levels and neutrophil counts in the cerebrospinal fluid were proven to be related by Spearman's rank correlation coefficient analysis (r = .724). These elevations of G-CSF levels at inflammation sites associated with bacterial meningitis may indicate that G-CSF plays an important role in the combat of bacterial infections." @default.
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• W2271525555 date "1991-05-15" @default.
• W2271525555 modified "2023-09-27" @default.
• W2271525555 title "Granulocyte colony-stimulating factor in cerebrospinal fluid from patients with meningitis" @default.
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• W2271525555 doi "https://doi.org/10.1182/blood.v77.10.2214.2214" @default.
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