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- W2271602246 abstract "Allergen immunotherapy is effective in patients with allergic rhinitis (AR) and, unlike antiallergic drugs, has been shown to modify the underlying cause of the disease, with proved long-term benefits. Subcutaneous immunotherapy (SCIT) has been the gold standard, whereas sublingual immunotherapy (SLIT) has emerged as an effective and safe alternative. Previous Cochrane systematic reviews and meta-analyses have confirmed that both SLIT and SCIT are effective in patients with seasonal AR, whereas evidence for their efficacy in patients with perennial disease has been less convincing. Recent large, adequately powered trials have demonstrated reductions in both symptoms and use of rescue medication in patients with seasonal and those with perennial AR. Here we appraise evidence for SCIT versus SLIT based on indirect evidence from Cochrane reviews and recent well-powered double-blind, randomized controlled trials versus placebo and the limited direct evidence available from randomized blind head-to-head comparisons. At present, based on an overall balance of efficacy and side effects, the patient is in equipoise. Pending definitive comparative trials, choice might be determined largely by the local availability of SCIT and SLIT products of proved value and personal (patient) preference." @default.
- W2271602246 created "2016-06-24" @default.
- W2271602246 creator A5043192106 @default.
- W2271602246 creator A5070488224 @default.
- W2271602246 date "2016-02-01" @default.
- W2271602246 modified "2023-10-15" @default.
- W2271602246 title "Sublingual or subcutaneous immunotherapy for allergic rhinitis?" @default.
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- W2271602246 cites W1608960808 @default.
- W2271602246 cites W1614858694 @default.
- W2271602246 cites W1855154847 @default.
- W2271602246 cites W1875082978 @default.
- W2271602246 cites W188765527 @default.
- W2271602246 cites W1968234331 @default.
- W2271602246 cites W1971110885 @default.
- W2271602246 cites W1980806499 @default.
- W2271602246 cites W1984062235 @default.
- W2271602246 cites W1984360617 @default.
- W2271602246 cites W1995211939 @default.
- W2271602246 cites W1996904229 @default.
- W2271602246 cites W1998970638 @default.
- W2271602246 cites W2005107727 @default.
- W2271602246 cites W2005586401 @default.
- W2271602246 cites W2005704343 @default.
- W2271602246 cites W2010998136 @default.
- W2271602246 cites W2013440291 @default.
- W2271602246 cites W2014406460 @default.
- W2271602246 cites W2018483969 @default.
- W2271602246 cites W2022429437 @default.
- W2271602246 cites W2024737544 @default.
- W2271602246 cites W2028803867 @default.
- W2271602246 cites W2036095293 @default.
- W2271602246 cites W2036437735 @default.
- W2271602246 cites W2037187709 @default.
- W2271602246 cites W2044792690 @default.
- W2271602246 cites W2049540404 @default.
- W2271602246 cites W2057823902 @default.
- W2271602246 cites W2060411425 @default.
- W2271602246 cites W2065738222 @default.
- W2271602246 cites W2066505403 @default.
- W2271602246 cites W2074474404 @default.
- W2271602246 cites W2074942491 @default.
- W2271602246 cites W2081260269 @default.
- W2271602246 cites W2084414920 @default.
- W2271602246 cites W2088213211 @default.
- W2271602246 cites W2090363075 @default.
- W2271602246 cites W2091425406 @default.
- W2271602246 cites W2091755039 @default.
- W2271602246 cites W2092203805 @default.
- W2271602246 cites W2093740248 @default.
- W2271602246 cites W2093792384 @default.
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- W2271602246 cites W2113389712 @default.
- W2271602246 cites W2114743889 @default.
- W2271602246 cites W2116810696 @default.
- W2271602246 cites W2121760095 @default.
- W2271602246 cites W2129849056 @default.
- W2271602246 cites W2131250882 @default.
- W2271602246 cites W2142388937 @default.
- W2271602246 cites W2142589482 @default.
- W2271602246 cites W2153804236 @default.
- W2271602246 cites W2154126700 @default.
- W2271602246 cites W2154185834 @default.
- W2271602246 cites W2158341249 @default.
- W2271602246 cites W2164132449 @default.
- W2271602246 cites W2164416536 @default.
- W2271602246 cites W2165126386 @default.
- W2271602246 cites W2312829609 @default.
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- W2271602246 cites W4229553561 @default.
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- W2271602246 doi "https://doi.org/10.1016/j.jaci.2015.12.1298" @default.
- W2271602246 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26853126" @default.
- W2271602246 hasPublicationYear "2016" @default.
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