FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2271612737> ?p ?o ?g. }

• W2271612737 endingPage "1362" @default.
• W2271612737 startingPage "1355" @default.
• W2271612737 abstract "Animal models of Human African Trypanosomiasis (HAT) have been developed to understand the pathogenic mechanisms leading to the passage into the neurological phase, most of them referring to histological aspects but not clinical or behavioral data. Our study aimed at defining simple clinical and/or behavioral markers of the passage between the hemolymphatic phase and the meningo-encephalitic stage of the disease. Sprague-Dawley rats (n=24) were infected with Trypanosoma brucei brucei AnTat 1.1E. Food intake and body weight were measured daily from the day of infection until death. Hematocrit was measured twice a week. Behavioral disturbances were evaluated through an Open-field test. A sudden weight loss occurred on the twelfth day after infection, due to a significant drop of food intake starting two days before. The rats developed an anemic state shown by the hematocrit measurements. The Open-field test showed them to be less active and reactive as soon as the second week after infestation. A complementary histological study observed trypanosomes and inflammatory cells in the choroid plexus at the same period. These results are in favor of central nervous system functional disturbances. The observed weight loss is discussed as being a parameter of the entry in the meningo-encephalitic phase. The rat model reproduces neurological symptoms observed in the human disease and may prove to be useful for further neurohistological and therapeutic studies." @default.
• W2271612737 created "2016-06-24" @default.
• W2271612737 creator A5017043364 @default.
• W2271612737 creator A5018470387 @default.
• W2271612737 creator A5029713442 @default.
• W2271612737 creator A5030623959 @default.
• W2271612737 creator A5032490096 @default.
• W2271612737 creator A5033623506 @default.
• W2271612737 creator A5070728556 @default.
• W2271612737 creator A5077043880 @default.
• W2271612737 creator A5089411815 @default.
• W2271612737 creator A5091460840 @default.
• W2271612737 date "2003-12-01" @default.
• W2271612737 modified "2023-10-16" @default.
• W2271612737 title "Clinical Follow-Up in the Rat Experimental Model of African-Trypanosomiasis" @default.
• W2271612737 cites W139562766 @default.
• W2271612737 cites W1977400775 @default.
• W2271612737 cites W1980757661 @default.
• W2271612737 cites W1992539245 @default.
• W2271612737 cites W1993434632 @default.
• W2271612737 cites W2003578711 @default.
• W2271612737 cites W2004633550 @default.
• W2271612737 cites W2016154498 @default.
• W2271612737 cites W2017923904 @default.
• W2271612737 cites W2018045802 @default.
• W2271612737 cites W2021397306 @default.
• W2271612737 cites W2023287842 @default.
• W2271612737 cites W2044102213 @default.
• W2271612737 cites W2047183254 @default.
• W2271612737 cites W2064933733 @default.
• W2271612737 cites W2066339186 @default.
• W2271612737 cites W2073074202 @default.
• W2271612737 cites W2087121252 @default.
• W2271612737 cites W2091360856 @default.
• W2271612737 cites W2113919459 @default.
• W2271612737 cites W2119230889 @default.
• W2271612737 cites W2122462682 @default.
• W2271612737 cites W2124608949 @default.
• W2271612737 cites W2126390000 @default.
• W2271612737 cites W2137175087 @default.
• W2271612737 cites W2315594089 @default.
• W2271612737 cites W2332613468 @default.
• W2271612737 cites W2333494189 @default.
• W2271612737 cites W2408530918 @default.
• W2271612737 cites W2419519065 @default.
• W2271612737 cites W28172040 @default.
• W2271612737 cites W4240710699 @default.
• W2271612737 cites W4252048163 @default.
• W2271612737 doi "https://doi.org/10.1177/153537020322801114" @default.
• W2271612737 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/14681551" @default.
• W2271612737 hasPublicationYear "2003" @default.
• W2271612737 type Work @default.
• W2271612737 sameAs 2271612737 @default.
• W2271612737 citedByCount "31" @default.
• W2271612737 countsByYear W22716127372012 @default.
• W2271612737 countsByYear W22716127372013 @default.
• W2271612737 countsByYear W22716127372014 @default.
• W2271612737 countsByYear W22716127372015 @default.
• W2271612737 countsByYear W22716127372016 @default.
• W2271612737 countsByYear W22716127372017 @default.
• W2271612737 countsByYear W22716127372018 @default.
• W2271612737 countsByYear W22716127372019 @default.
• W2271612737 countsByYear W22716127372021 @default.
• W2271612737 countsByYear W22716127372023 @default.
• W2271612737 crossrefType "journal-article" @default.
• W2271612737 hasAuthorship W2271612737A5017043364 @default.
• W2271612737 hasAuthorship W2271612737A5018470387 @default.
• W2271612737 hasAuthorship W2271612737A5029713442 @default.
• W2271612737 hasAuthorship W2271612737A5030623959 @default.
• W2271612737 hasAuthorship W2271612737A5032490096 @default.
• W2271612737 hasAuthorship W2271612737A5033623506 @default.
• W2271612737 hasAuthorship W2271612737A5070728556 @default.
• W2271612737 hasAuthorship W2271612737A5077043880 @default.
• W2271612737 hasAuthorship W2271612737A5089411815 @default.
• W2271612737 hasAuthorship W2271612737A5091460840 @default.
• W2271612737 hasConcept C104317684 @default.
• W2271612737 hasConcept C126322002 @default.
• W2271612737 hasConcept C142724271 @default.
• W2271612737 hasConcept C2778117688 @default.
• W2271612737 hasConcept C2778143080 @default.
• W2271612737 hasConcept C2778792689 @default.
• W2271612737 hasConcept C2779085643 @default.
• W2271612737 hasConcept C2779502636 @default.
• W2271612737 hasConcept C2780959883 @default.
• W2271612737 hasConcept C42407357 @default.
• W2271612737 hasConcept C511355011 @default.
• W2271612737 hasConcept C544821477 @default.
• W2271612737 hasConcept C55493867 @default.
• W2271612737 hasConcept C71924100 @default.
• W2271612737 hasConcept C86803240 @default.
• W2271612737 hasConceptScore W2271612737C104317684 @default.
• W2271612737 hasConceptScore W2271612737C126322002 @default.
• W2271612737 hasConceptScore W2271612737C142724271 @default.
• W2271612737 hasConceptScore W2271612737C2778117688 @default.
• W2271612737 hasConceptScore W2271612737C2778143080 @default.
• W2271612737 hasConceptScore W2271612737C2778792689 @default.
• W2271612737 hasConceptScore W2271612737C2779085643 @default.
• W2271612737 hasConceptScore W2271612737C2779502636 @default.

• next