Matches in SemOpenAlex for { <https://semopenalex.org/work/W2272181882> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2272181882 endingPage "8" @default.
- W2272181882 startingPage "1" @default.
- W2272181882 abstract "Background and Aims: Saliva is one of the protective factors against gastroesophageal reflux. However, its actual role in patients with gastroesophageal reflux disease (GERD) particularly in terms of mucosal protection requires elucidation. Present study attempted to know the distinct protective role of saliva in esophageal mucosal protection. Materials and Methods: Fifty-four patients with typical GERD symptoms were consecutively enrolled. Personal history for non-steroidal anti-inflammatory drugs (NSAIDs) use, drinking tea, coffee and alcohol and smoking status was recorded. Stimulated saliva secretion was collected from each subject and its epidermal growth factor (EGF) and prostaglandin (PG) PGE1/PGE2 were determined. Upper gastrointestinal (GI) panendoscopy was performed to determine which patients had erosive esophagitis (EE) (n=27) and non-erosive reflux disease (NERD) (n=27). Helicobacter pylori (Hp) infection was checked and gastric juice pH was also assessed. Additionally, 27 non-GERD dyspeptic subjects were enrolled as controls for comparisons. Results: No significant differences were noted between EE patients and NERD patients in all variables including: age; gender; consumptions of tea, coffee or alcohol; smoking status; use of NSAIDs; Hp infection; gastric juice pH; rate of hiatal hernia; saliva secretion amount; salivary concentrations of PGE1/PGE2 and EGF, and salivary PGE1/ PGE2 and EGF output. However, EE patients had a significantly higher likelihood of hiatal hernia (48% vs. 19%), higher saliva secretion amount (1.82±0.67 vs. 1.33±0.36 ml/min) and salivary EGF output (3.8±1.5 vs. 2.5±0.9 ng/min) than controls (P＜0.05). Unlike EE patients, NERD patients did not have any significant differences from the control group for these variables. Conclusion: Patients with endoscopically evident EE had significantly increased salivary output. The result could not support that saliva play a critical role in protecting against the formation and severity of erosive esophagitis in our study model." @default.
- W2272181882 created "2016-06-24" @default.
- W2272181882 creator A5010407536 @default.
- W2272181882 creator A5024549249 @default.
- W2272181882 creator A5046698549 @default.
- W2272181882 creator A5054235677 @default.
- W2272181882 creator A5064580973 @default.
- W2272181882 creator A5091253658 @default.
- W2272181882 date "2006-03-01" @default.
- W2272181882 modified "2023-10-18" @default.
- W2272181882 title "Study of Salivary Function in Patients with Gastroesophageal Reflux Disease" @default.
- W2272181882 doi "https://doi.org/10.6557/gjt.200603_23(1).0001" @default.
- W2272181882 hasPublicationYear "2006" @default.
- W2272181882 type Work @default.
- W2272181882 sameAs 2272181882 @default.
- W2272181882 citedByCount "1" @default.
- W2272181882 countsByYear W22721818822019 @default.
- W2272181882 crossrefType "journal-article" @default.
- W2272181882 hasAuthorship W2272181882A5010407536 @default.
- W2272181882 hasAuthorship W2272181882A5024549249 @default.
- W2272181882 hasAuthorship W2272181882A5046698549 @default.
- W2272181882 hasAuthorship W2272181882A5054235677 @default.
- W2272181882 hasAuthorship W2272181882A5064580973 @default.
- W2272181882 hasAuthorship W2272181882A5091253658 @default.
- W2272181882 hasConcept C126322002 @default.
- W2272181882 hasConcept C2776409635 @default.
- W2272181882 hasConcept C2777014526 @default.
- W2272181882 hasConcept C2777683962 @default.
- W2272181882 hasConcept C2778197217 @default.
- W2272181882 hasConcept C2779134260 @default.
- W2272181882 hasConcept C2779920096 @default.
- W2272181882 hasConcept C43270747 @default.
- W2272181882 hasConcept C504460877 @default.
- W2272181882 hasConcept C71924100 @default.
- W2272181882 hasConcept C90924648 @default.
- W2272181882 hasConceptScore W2272181882C126322002 @default.
- W2272181882 hasConceptScore W2272181882C2776409635 @default.
- W2272181882 hasConceptScore W2272181882C2777014526 @default.
- W2272181882 hasConceptScore W2272181882C2777683962 @default.
- W2272181882 hasConceptScore W2272181882C2778197217 @default.
- W2272181882 hasConceptScore W2272181882C2779134260 @default.
- W2272181882 hasConceptScore W2272181882C2779920096 @default.
- W2272181882 hasConceptScore W2272181882C43270747 @default.
- W2272181882 hasConceptScore W2272181882C504460877 @default.
- W2272181882 hasConceptScore W2272181882C71924100 @default.
- W2272181882 hasConceptScore W2272181882C90924648 @default.
- W2272181882 hasIssue "1" @default.
- W2272181882 hasLocation W22721818821 @default.
- W2272181882 hasOpenAccess W2272181882 @default.
- W2272181882 hasPrimaryLocation W22721818821 @default.
- W2272181882 hasRelatedWork W1502413160 @default.
- W2272181882 hasRelatedWork W2017154225 @default.
- W2272181882 hasRelatedWork W2047182909 @default.
- W2272181882 hasRelatedWork W2064400183 @default.
- W2272181882 hasRelatedWork W2080205848 @default.
- W2272181882 hasRelatedWork W2347956187 @default.
- W2272181882 hasRelatedWork W2353552871 @default.
- W2272181882 hasRelatedWork W2353857922 @default.
- W2272181882 hasRelatedWork W2382076210 @default.
- W2272181882 hasRelatedWork W2391471968 @default.
- W2272181882 hasRelatedWork W2395470012 @default.
- W2272181882 hasRelatedWork W2413799895 @default.
- W2272181882 hasRelatedWork W2414318019 @default.
- W2272181882 hasRelatedWork W2417495893 @default.
- W2272181882 hasRelatedWork W2762237010 @default.
- W2272181882 hasRelatedWork W3001890836 @default.
- W2272181882 hasRelatedWork W3030451991 @default.
- W2272181882 hasRelatedWork W3145292628 @default.
- W2272181882 hasRelatedWork W3201482844 @default.
- W2272181882 hasRelatedWork W2496863340 @default.
- W2272181882 hasVolume "23" @default.
- W2272181882 isParatext "false" @default.
- W2272181882 isRetracted "false" @default.
- W2272181882 magId "2272181882" @default.
- W2272181882 workType "article" @default.