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- W2272189385 abstract "We report the first successful treatment with the thrombopoietin receptor mimetic eltrombopag in a patient with severe aplastic anaemia (SAA) associated with HIV infection, thereby avoiding the use of standard immunosuppressive agents for treatment of SAA. Eltrombopag induced a trilineage haematological response. We also show that eltrombopag had an immunomodulatory role with a decrease in proinflammatory T helpers (Th1 and Th17 cells) with increased T-regulatory cell/T-helper ratio, thus contributing to recovery of haemopoiesis." @default.
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- W2272189385 date "2014-11-28" @default.
- W2272189385 modified "2023-09-23" @default.
- W2272189385 title "Successful treatment of aplastic anaemia associated with HIV infection with eltrombopag" @default.
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- W2272189385 doi "https://doi.org/10.1097/qad.0000000000000504" @default.
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