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- W2272300979 abstract "Introduction: The obesity hypoventilation syndrome (OHS) is a severe sleep related breathing disorder, with obstructive sleep apnea syndrome (OSAS) as the predominant sleeping pattern. It is often accompanied by multiple organ tract involvement. In OSAS, the interaction with metabolic syndrome is well studied. In OHS however, it is unclear whether the severity of disease has consequences for the occurrence and severity of metabolic syndrome. We evaluated the presence of evidence based knowledge. Methods: A systematic Pubmed and Cochrane search was performed, final check 24th February 2011, for metabolic syndrome in concurrence with OSAS and OHS, and related terms and synonyms in title and abstract (exclusion criterion: duplicates). The final data set was achieved by elimination of studies that contained predefined criteria: animal studies, studies Results: 767 initial hits were found in OSAS, versus 273 for OHS. After the predefined elimination strategy, 171 remained, containing 5 RCT9s for OSAS, versus 6 studies, without any RCT, for OHS (Fischer exact p Conclusion: A markedly lower number of hits was found for metabolic syndrome in OHS, as compared to OSAS. Within the complexity of clinical features in OHS, the metabolic syndrome seems to be an unexplored area in research." @default.
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- W2272300979 date "2011-09-01" @default.
- W2272300979 modified "2023-09-28" @default.
- W2272300979 title "The lack of evidence based knowledge of metabolic syndrome in obesity hypoventilation syndrome" @default.
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