FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2272597274> ?p ?o ?g. }

• W2272597274 endingPage "10" @default.
• W2272597274 startingPage "1" @default.
• W2272597274 abstract "While vitamin D 3 is recognized as a neuroactive steroid affecting both brain development and function, efficient analytical method in determining vitamin D 3 metabolites in the brain tissue is still lacking, and the relationship of vitamin D 3 status between serum and brain remains elusive. Therefore, we developed a novel analysis method by using high performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) to simultaneously quantify the concentrations of 25-hydroxyvitamin D 3 (25(OH)D 3 ) and 24,25-dihydroxyvitamin D 3 (24,25(OH) 2 D 3 ) in the serum and brain of rats fed with different dose of vitamin D 3 . We further investigated whether variations of serum vitamin D 3 metabolites could affect vitamin D 3 metabolite levels in the brain. Serum and brain tissue were analyzed by HPLC-MS/MS with electrospray ionization following derivatization with 4-phenyl-1,2,4-triazoline-3,5-dione (PTAD). The method is highly sensitive, specific, and accurate to quantify 25(OH)D 3 and 24,25(OH) 2 D 3 in animal brain tissue. Vitamin D 3 metabolites in brain tissue were significantly lower in rats fed with a vitamin D deficiency diet than in rats fed with high vitamin D 3 diet. There was also a strong correlation of vitamin D 3 metabolites in serum and brain. These results indicate that vitamin D 3 status in serum affects bioavailability of vitamin D 3 metabolites in the brain." @default.
• W2272597274 created "2016-06-24" @default.
• W2272597274 creator A5000128482 @default.
• W2272597274 creator A5006019048 @default.
• W2272597274 creator A5022104747 @default.
• W2272597274 creator A5032003297 @default.
• W2272597274 creator A5037827711 @default.
• W2272597274 creator A5058473496 @default.
• W2272597274 creator A5064832836 @default.
• W2272597274 creator A5065598852 @default.
• W2272597274 creator A5088170440 @default.
• W2272597274 date "2015-01-01" @default.
• W2272597274 modified "2023-10-16" @default.
• W2272597274 title "Simultaneous Quantification of 25-Hydroxyvitamin D₃and 24,25-Dihydroxyvitamin D₃in Rats Shows Strong Correlations between Serum and Brain Tissue Levels" @default.
• W2272597274 cites W1520616223 @default.
• W2272597274 cites W1750476262 @default.
• W2272597274 cites W1979305718 @default.
• W2272597274 cites W1993342435 @default.
• W2272597274 cites W1998754189 @default.
• W2272597274 cites W2013517159 @default.
• W2272597274 cites W2015334615 @default.
• W2272597274 cites W2017857772 @default.
• W2272597274 cites W2018797048 @default.
• W2272597274 cites W2019015726 @default.
• W2272597274 cites W2025464272 @default.
• W2272597274 cites W2028927099 @default.
• W2272597274 cites W2034411968 @default.
• W2272597274 cites W2047660235 @default.
• W2272597274 cites W2049102648 @default.
• W2272597274 cites W2051909250 @default.
• W2272597274 cites W2060053138 @default.
• W2272597274 cites W2064083010 @default.
• W2272597274 cites W2069163972 @default.
• W2272597274 cites W2080060312 @default.
• W2272597274 cites W2090710011 @default.
• W2272597274 cites W2093158385 @default.
• W2272597274 cites W2101714022 @default.
• W2272597274 cites W2103586572 @default.
• W2272597274 cites W2110797318 @default.
• W2272597274 cites W2120007830 @default.
• W2272597274 cites W2124070987 @default.
• W2272597274 cites W2124603205 @default.
• W2272597274 cites W2151255529 @default.
• W2272597274 cites W2169605456 @default.
• W2272597274 cites W2170647381 @default.
• W2272597274 cites W2441420844 @default.
• W2272597274 cites W97368028 @default.
• W2272597274 doi "https://doi.org/10.1155/2015/296531" @default.
• W2272597274 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4680053" @default.
• W2272597274 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26713090" @default.
• W2272597274 hasPublicationYear "2015" @default.
• W2272597274 type Work @default.
• W2272597274 sameAs 2272597274 @default.
• W2272597274 citedByCount "12" @default.
• W2272597274 countsByYear W22725972742016 @default.
• W2272597274 countsByYear W22725972742018 @default.
• W2272597274 countsByYear W22725972742019 @default.
• W2272597274 countsByYear W22725972742021 @default.
• W2272597274 countsByYear W22725972742022 @default.
• W2272597274 countsByYear W22725972742023 @default.
• W2272597274 crossrefType "journal-article" @default.
• W2272597274 hasAuthorship W2272597274A5000128482 @default.
• W2272597274 hasAuthorship W2272597274A5006019048 @default.
• W2272597274 hasAuthorship W2272597274A5022104747 @default.
• W2272597274 hasAuthorship W2272597274A5032003297 @default.
• W2272597274 hasAuthorship W2272597274A5037827711 @default.
• W2272597274 hasAuthorship W2272597274A5058473496 @default.
• W2272597274 hasAuthorship W2272597274A5064832836 @default.
• W2272597274 hasAuthorship W2272597274A5065598852 @default.
• W2272597274 hasAuthorship W2272597274A5088170440 @default.
• W2272597274 hasBestOaLocation W22725972741 @default.
• W2272597274 hasConcept C124490489 @default.
• W2272597274 hasConcept C126322002 @default.
• W2272597274 hasConcept C134018914 @default.
• W2272597274 hasConcept C153639570 @default.
• W2272597274 hasConcept C179998833 @default.
• W2272597274 hasConcept C181389837 @default.
• W2272597274 hasConcept C185592680 @default.
• W2272597274 hasConcept C2776923573 @default.
• W2272597274 hasConcept C2776940978 @default.
• W2272597274 hasConcept C2777477808 @default.
• W2272597274 hasConcept C2779740938 @default.
• W2272597274 hasConcept C2986936838 @default.
• W2272597274 hasConcept C43617362 @default.
• W2272597274 hasConcept C71924100 @default.
• W2272597274 hasConcept C98274493 @default.
• W2272597274 hasConceptScore W2272597274C124490489 @default.
• W2272597274 hasConceptScore W2272597274C126322002 @default.
• W2272597274 hasConceptScore W2272597274C134018914 @default.
• W2272597274 hasConceptScore W2272597274C153639570 @default.
• W2272597274 hasConceptScore W2272597274C179998833 @default.
• W2272597274 hasConceptScore W2272597274C181389837 @default.
• W2272597274 hasConceptScore W2272597274C185592680 @default.
• W2272597274 hasConceptScore W2272597274C2776923573 @default.
• W2272597274 hasConceptScore W2272597274C2776940978 @default.
• W2272597274 hasConceptScore W2272597274C2777477808 @default.
• W2272597274 hasConceptScore W2272597274C2779740938 @default.
• W2272597274 hasConceptScore W2272597274C2986936838 @default.

• next