Matches in SemOpenAlex for { <https://semopenalex.org/work/W2272804922> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W2272804922 endingPage "79" @default.
- W2272804922 startingPage "61" @default.
- W2272804922 abstract "An increasing body of evidence from both animal models and human specimens suggests that apoptosis or programmed cell death is a major event in the pathophysiology of atherosclerosis. Although the significance of apoptosis in atherosclerosis remains unclear, it has been proposed that apoptotic cell death contributes to plaque instability, rupture and thrombus formation. In this study, we have outlined some of our most recent results concerning initiation of apoptosis in atherosclerosis with a special focus on oxidative DNA and RNA damage. Furthermore, we provide a detailed picture of the pro- and anti-apoptotic genes/proteins that are involved during the initiation of cell death in atherosclerotic plaques by using a combination of established immunohistochemical stainings and recent molecular biology techniques. Our data suggest that smooth muscle cells and macrophages in atherosclerotic plaques express a different panel of apoptosis-related genes in response to proapoptotic stimuli. Although this may seem a promising starting-point for the development of anti-atherogenic drugs, it remains to be determined whether modulation of apoptosis can become a clinically important approach to influence plaque progression." @default.
- W2272804922 created "2016-06-24" @default.
- W2272804922 creator A5050123381 @default.
- W2272804922 creator A5076009877 @default.
- W2272804922 date "2004-01-01" @default.
- W2272804922 modified "2023-09-29" @default.
- W2272804922 title "Apoptosis in atheroclerosis: implications for plaque destabilization." @default.
- W2272804922 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15074082" @default.
- W2272804922 hasPublicationYear "2004" @default.
- W2272804922 type Work @default.
- W2272804922 sameAs 2272804922 @default.
- W2272804922 citedByCount "5" @default.
- W2272804922 countsByYear W22728049222012 @default.
- W2272804922 countsByYear W22728049222013 @default.
- W2272804922 crossrefType "journal-article" @default.
- W2272804922 hasAuthorship W2272804922A5050123381 @default.
- W2272804922 hasAuthorship W2272804922A5076009877 @default.
- W2272804922 hasConcept C142724271 @default.
- W2272804922 hasConcept C190283241 @default.
- W2272804922 hasConcept C203014093 @default.
- W2272804922 hasConcept C2779179121 @default.
- W2272804922 hasConcept C31573885 @default.
- W2272804922 hasConcept C502942594 @default.
- W2272804922 hasConcept C54355233 @default.
- W2272804922 hasConcept C71924100 @default.
- W2272804922 hasConcept C86803240 @default.
- W2272804922 hasConcept C95444343 @default.
- W2272804922 hasConceptScore W2272804922C142724271 @default.
- W2272804922 hasConceptScore W2272804922C190283241 @default.
- W2272804922 hasConceptScore W2272804922C203014093 @default.
- W2272804922 hasConceptScore W2272804922C2779179121 @default.
- W2272804922 hasConceptScore W2272804922C31573885 @default.
- W2272804922 hasConceptScore W2272804922C502942594 @default.
- W2272804922 hasConceptScore W2272804922C54355233 @default.
- W2272804922 hasConceptScore W2272804922C71924100 @default.
- W2272804922 hasConceptScore W2272804922C86803240 @default.
- W2272804922 hasConceptScore W2272804922C95444343 @default.
- W2272804922 hasIssue "1" @default.
- W2272804922 hasLocation W22728049221 @default.
- W2272804922 hasOpenAccess W2272804922 @default.
- W2272804922 hasPrimaryLocation W22728049221 @default.
- W2272804922 hasRelatedWork W1956140656 @default.
- W2272804922 hasRelatedWork W1982308850 @default.
- W2272804922 hasRelatedWork W1985507373 @default.
- W2272804922 hasRelatedWork W1987808828 @default.
- W2272804922 hasRelatedWork W2003393278 @default.
- W2272804922 hasRelatedWork W2005134793 @default.
- W2272804922 hasRelatedWork W2066245615 @default.
- W2272804922 hasRelatedWork W2085143181 @default.
- W2272804922 hasRelatedWork W2089307883 @default.
- W2272804922 hasRelatedWork W2091414184 @default.
- W2272804922 hasRelatedWork W2091797157 @default.
- W2272804922 hasRelatedWork W2110136648 @default.
- W2272804922 hasRelatedWork W2115619586 @default.
- W2272804922 hasRelatedWork W2143708081 @default.
- W2272804922 hasRelatedWork W2151203560 @default.
- W2272804922 hasRelatedWork W2166431193 @default.
- W2272804922 hasRelatedWork W2278594366 @default.
- W2272804922 hasRelatedWork W2386474412 @default.
- W2272804922 hasRelatedWork W2460403048 @default.
- W2272804922 hasRelatedWork W413994578 @default.
- W2272804922 hasVolume "66" @default.
- W2272804922 isParatext "false" @default.
- W2272804922 isRetracted "false" @default.
- W2272804922 magId "2272804922" @default.
- W2272804922 workType "article" @default.