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- W2272827384 abstract "Avenanthramides play a role as phytoalexins in oat. Recently, various bioactivities have been found in avenanthramides as an antioxidant activity, anti-inflammatory, anti-atherogenic and anti‑proliferative effect. In this study, the optimal conditions for the extraction of avenanthramides 2c, 2p and 2f from oat grain, cultivar Avenuda, were determined using response surface methodology (RSM). The effects of three independent variables (methanol concentration, extraction temperature and time) on the yield of aventhramides were investigated. A second-order polynomial model adequately fitted the experimental data with the R2 values of 0.959, 0.970 and 0.984 for the response of avenanthramides 2c, 2p and 2f, respectively. The optimization method which combined RSM with desirability function was chosen to find the best extraction conditions. The optimal conditions for the highest yield of avenanthramides were a methanol concentration of 70%, extraction temperature 55 °C and time 165 min. Under these conditions, the yields of avenanthramides 2c, 2p and 2f were 9.70 ± 0.38 mg kg-1, 10.05 ± 0.44 mg kg-1 and 19.18 ± 0.80 mg kg-1 oat grain, respectively." @default.
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- W2272827384 date "2015-01-01" @default.
- W2272827384 modified "2023-09-27" @default.
- W2272827384 title "Optimization of Parameters for Extraction of Avenanthramides from Oat (<i>Avena sativa</i>L.) Grain Using Response Surface Methodology (RSM)" @default.
- W2272827384 cites W2044771513 @default.
- W2272827384 doi "https://doi.org/10.5935/0103-5053.20150233" @default.
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