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- W2273150064 abstract "The clinical features and immunological studies of 20 women who have exposed to silicone by either direct injection or implantation were evaluated in the past year. We included the followings as the variables in this study: complete physical examination, immunoglobulins (IgG, IgM, IgA), complements (C3, C4), rheumatoid factor, antinuclear antigen (ANA), anti DNA antigen, lymphocyte subpopulations, clinical features, and surgical exploration. The results reveal all patients who have exposed to silicone show some degree of immunologic abnormalities, but most of them were asymptomatic. High ANA titers were present in 11 of these 14 patients. It remain unclear how silicone interacts with the immune system. But we did made one important observation: ANAs are closely associated with the silicone exposed populations. Further studies are needed to see whether this relation is one of cause and effect and whether ANAs might be early serological markers preceding development of autoimmune symptoms." @default.
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- W2273150064 date "1995-03-01" @default.
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- W2273150064 title "Immunologic Studies in a Silicone Exposed Population a Preliminary Report" @default.
- W2273150064 doi "https://doi.org/10.7096/jprsa.199503.0035" @default.
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