FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2273250957> ?p ?o ?g. }

• W2273250957 endingPage "H1104" @default.
• W2273250957 startingPage "H1098" @default.
• W2273250957 abstract "The effects of pulsatility in blood flow on endothelium-derived nitric oxide (EDNO) release in the peripheral vasculature were investigated. The basal and flow-stimulated EDNO release were compared between pulsatile and nonpulsatile systemic flows before and after the administration of NO synthase inhibitor N(G)-monomethyl-L-arginine (L-NMMA). Peripheral vascular resistance (PVR) was significantly lower in pulsatile flow than in nonpulsatile flow, but this difference disappeared after L-NMMA. The percent increase in PVR by L-NMMA was significantly larger in pulsatile flow. In reactive hyperemia in the hindlimb, the peak flow did not differ; however, both the repayment flow and the duration were significantly larger in pulsatile flow. Percent changes of these parameters by L-NMMA were significantly larger in pulsatile flow. These data indicated that pulsatility significantly enhances the basal and flow-stimulated EDNO release in the peripheral vasculature under in vivo conditions. We also studied the involvement of the Ca(2+)-dependent and Ca(2+)-independent pathways in flow-induced vasodilation using calmodulin inhibitor calmidazolium and tyrosine kinase inhibitor erbstatin A. PVR was significantly elevated by erbstatin A but not by calmidazolium, suggesting that flow-induced vasodilation was largely caused by tyrosine kinase inhibitor-sensitive activation of NO synthase." @default.
• W2273250957 created "2016-06-24" @default.
• W2273250957 creator A5066745254 @default.
• W2273250957 creator A5076314944 @default.
• W2273250957 creator A5077772927 @default.
• W2273250957 creator A5082067448 @default.
• W2273250957 creator A5091096146 @default.
• W2273250957 date "2000-04-01" @default.
• W2273250957 modified "2023-09-30" @default.
• W2273250957 title "Pulsatile flow enhances endothelium-derived nitric oxide release in the peripheral vasculature" @default.
• W2273250957 cites W1924909341 @default.
• W2273250957 cites W1965148671 @default.
• W2273250957 cites W1976944744 @default.
• W2273250957 cites W1978873292 @default.
• W2273250957 cites W1983964547 @default.
• W2273250957 cites W1985093096 @default.
• W2273250957 cites W1986733870 @default.
• W2273250957 cites W1996728375 @default.
• W2273250957 cites W2014728018 @default.
• W2273250957 cites W2022365880 @default.
• W2273250957 cites W2024450698 @default.
• W2273250957 cites W2025445144 @default.
• W2273250957 cites W2068247383 @default.
• W2273250957 cites W2070542275 @default.
• W2273250957 cites W2083611167 @default.
• W2273250957 cites W2091181219 @default.
• W2273250957 cites W2092478589 @default.
• W2273250957 cites W2132440861 @default.
• W2273250957 cites W2145565857 @default.
• W2273250957 cites W2145752889 @default.
• W2273250957 cites W2262423141 @default.
• W2273250957 cites W2341645605 @default.
• W2273250957 cites W23664147 @default.
• W2273250957 cites W2396749944 @default.
• W2273250957 cites W2405790580 @default.
• W2273250957 cites W2410780138 @default.
• W2273250957 cites W2419243513 @default.
• W2273250957 cites W2419278577 @default.
• W2273250957 doi "https://doi.org/10.1152/ajpheart.2000.278.4.h1098" @default.
• W2273250957 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/10749703" @default.
• W2273250957 hasPublicationYear "2000" @default.
• W2273250957 type Work @default.
• W2273250957 sameAs 2273250957 @default.
• W2273250957 citedByCount "88" @default.
• W2273250957 countsByYear W22732509572012 @default.
• W2273250957 countsByYear W22732509572013 @default.
• W2273250957 countsByYear W22732509572014 @default.
• W2273250957 countsByYear W22732509572015 @default.
• W2273250957 countsByYear W22732509572016 @default.
• W2273250957 countsByYear W22732509572017 @default.
• W2273250957 countsByYear W22732509572018 @default.
• W2273250957 countsByYear W22732509572020 @default.
• W2273250957 countsByYear W22732509572021 @default.
• W2273250957 countsByYear W22732509572022 @default.
• W2273250957 countsByYear W22732509572023 @default.
• W2273250957 crossrefType "journal-article" @default.
• W2273250957 hasAuthorship W2273250957A5066745254 @default.
• W2273250957 hasAuthorship W2273250957A5076314944 @default.
• W2273250957 hasAuthorship W2273250957A5077772927 @default.
• W2273250957 hasAuthorship W2273250957A5082067448 @default.
• W2273250957 hasAuthorship W2273250957A5091096146 @default.
• W2273250957 hasBestOaLocation W22732509571 @default.
• W2273250957 hasConcept C120770815 @default.
• W2273250957 hasConcept C126322002 @default.
• W2273250957 hasConcept C134018914 @default.
• W2273250957 hasConcept C178853913 @default.
• W2273250957 hasConcept C185592680 @default.
• W2273250957 hasConcept C2776992346 @default.
• W2273250957 hasConcept C2777622882 @default.
• W2273250957 hasConcept C2908937200 @default.
• W2273250957 hasConcept C3019128504 @default.
• W2273250957 hasConcept C519581460 @default.
• W2273250957 hasConcept C58245268 @default.
• W2273250957 hasConcept C71924100 @default.
• W2273250957 hasConcept C79191276 @default.
• W2273250957 hasConceptScore W2273250957C120770815 @default.
• W2273250957 hasConceptScore W2273250957C126322002 @default.
• W2273250957 hasConceptScore W2273250957C134018914 @default.
• W2273250957 hasConceptScore W2273250957C178853913 @default.
• W2273250957 hasConceptScore W2273250957C185592680 @default.
• W2273250957 hasConceptScore W2273250957C2776992346 @default.
• W2273250957 hasConceptScore W2273250957C2777622882 @default.
• W2273250957 hasConceptScore W2273250957C2908937200 @default.
• W2273250957 hasConceptScore W2273250957C3019128504 @default.
• W2273250957 hasConceptScore W2273250957C519581460 @default.
• W2273250957 hasConceptScore W2273250957C58245268 @default.
• W2273250957 hasConceptScore W2273250957C71924100 @default.
• W2273250957 hasConceptScore W2273250957C79191276 @default.
• W2273250957 hasIssue "4" @default.
• W2273250957 hasLocation W22732509571 @default.
• W2273250957 hasLocation W22732509572 @default.
• W2273250957 hasOpenAccess W2273250957 @default.
• W2273250957 hasPrimaryLocation W22732509571 @default.
• W2273250957 hasRelatedWork W1509822090 @default.
• W2273250957 hasRelatedWork W1971066171 @default.
• W2273250957 hasRelatedWork W2021330452 @default.
• W2273250957 hasRelatedWork W2029984904 @default.
• W2273250957 hasRelatedWork W2044700993 @default.

• next