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- W2273313450 abstract "The purpose of this study was to show the efficacy of olfactory stem cells for injured facial nerve reconstruction in a rat model.Olfactory stem cells were isolated from the olfactory mucosa of human participants. A 2-mm excision was performed on the right facial nerve of all rats. Reconstruction was performed with a conduit in group 1 (n = 9); a conduit and phosphate-buffered saline in group 2 (n = 9); and a conduit and labeled olfactory stem cell in group 3 (n = 9). Rats were followed for whisker movements and electroneuronography (ENoG) analyses.The whisker-movement scores for group 3 were significantly different from other groups (p < .001). ENoG showed that the amplitude values for group 3 were significantly different from group 1 and group 2 (p = .030; p < .001). Group 3 showed marked olfactory stem cell under a fluorescence microscope.This study suggests that olfactory stem cells may be used as a potent cellular therapy for accelerating the regeneration of peripheral nerve injuries. © 2016 Wiley Periodicals, Inc. Head Neck 38: E2011-E2020, 2016." @default.
- W2273313450 created "2016-06-24" @default.
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- W2273313450 date "2016-02-01" @default.
- W2273313450 modified "2023-10-01" @default.
- W2273313450 title "Human olfactory stem cells for injured facial nerve reconstruction in a rat model" @default.
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- W2273313450 doi "https://doi.org/10.1002/hed.24371" @default.
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