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• W2273345314 abstract "16035 Background: The pathology report of a prostatectomy specimen has critical prognostic significance. Given inconsistencies in processing and histological interpretations, the accuracy of pathological reports can vary between institutions. To determine main effect of institution on the review of specimens, we analyzed the robotic-assisted laparoscopic prostatectomy (RALP) outcomes of a single high volume surgeon who operated at two local institutions using the same technique and robotic team. Methods: We reviewed the pathologic outcomes of two IRB approved prospective databases for 400 consecutive RALP procedures performed by a single surgeon at two local institutions within the same 15 month period and compared the pathologic outcomes. Patients with seminal vesical invasion (pT3b), or node positive disease were excluded. Multivariate analysis was used to control for relevant preoperative oncologic risk factors. Results: Between July 2006 and September 2007, 200 RALPs were performed by a single surgeon at each of two separate institutions, for a total of 400 cases. A total of 384 patients met inclusion criteria, 191 from institution 1 (I-1) and 193 from institution 2 (I-2). Preoperative patient characteristics, including PSA, age, prostate size, and median biopsy Gleason, were similar between groups (I-1: 5.81ng/ml, 59.5y, 50.2g, 3+4; I-2: 5.96ng/ml, 58.4y, 52.4g, 3+4, respectively. There was no difference in clinical stages. Postoperatively, the overall positive margin rate for pT2 and pT3 tumors was 14% and 36%, respectively. Median pathologic gleason grade at both institutions was 4+3. However, I-1 was statistically more likely to upgrade Gleason scores than I-2 (p = 0.031). The same institution (I-1) also reported a significantly higher proportion of pT3 tumors (p = 0.01), but fewer pT3 positive margins (p < 0.001). There was no difference between the institutions in rate of pT2 positive margins (16% vs 11%, respectively, p=0.297). Conclusions: Given similar preoperative prostate sizes and PSA values, prostate cancer volumes were likely similar between the cohorts. We present a main effect of institution on pathological outcomes. Institutional differences in pathologic processing may account for some of the differences in rates of surgical margins. No significant financial relationships to disclose." @default.
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• W2273345314 date "2008-05-20" @default.
• W2273345314 modified "2023-09-25" @default.
• W2273345314 title "Interinstitutional variations in robotic prostatectomy pathologic outcomes for a single surgeon and team" @default.
• W2273345314 doi "https://doi.org/10.1200/jco.2008.26.15_suppl.16035" @default.
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