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- W2273365983 abstract "Objectives: In this study relationship between the levels of serum bilirubin and malondialdehyde was investigated in neonates with different stages of hyperbilirubinaemia. Methodology: The study included 110 neonates classified into four groups according the total bilirubin (TB) levels: G1 (n=31; TB 5 and 10 and 15 mg/dl). Results: The level of malondialdehyde was increased in stepwise manner in the hyperbilirubinaemia groups (G1=4.82 IU/l), (G2=9.21 IU/l), (G3=12.87 IU/l), and (G4=17 IU/l). A significant positive correlation was observed between malondialdehyde and bilirubin concentrations in the studied groups G1, G2, and G3 (P<0.001). A significant negative correlation was found between malondialdehyde and haemoglobin (P<0.001) in the same groups. Conclusion: The increases of serum total bilirubin levels in the neonate could be a response to excessive free radical generation and lipid peroxide formation. That may indicate the possible protective effect of antioxidant administration to the mother during pregnancy on the neonate. Serum MDA levels in the neonate could be used as an indicator or predictor of the severity of neonatal jaundice." @default.
- W2273365983 created "2016-06-24" @default.
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- W2273365983 date "2016-01-25" @default.
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- W2273365983 title "Serum levels of malondialdehyde and Bilirubin in neonates with different stages of hyperbilirubinaemia" @default.
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