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• W2273540556 abstract "Aim There is a large literature reporting risk factor analyses for poor neurodevelopment in children born very preterm (VPT: ≤32wks) or very low birthweight (VLBW: ≤1250g), which to date has not been formally summarized. The aim of this paper was to identify prognostic factors for cerebral palsy (CP) and motor impairment in children born VPT/VLBW. Method A systematic review was conducted using Medline, Embase, and Pyscinfo databases to identify studies published between 1 January 1990 and 1 June 2014 reporting multivariable prediction models for poor neurodevelopment in VPT/VLBW children (registration number CRD42014006943). Twenty-eight studies for motor outcomes were identified. Results There was strong evidence that intraventricular haemorrhage and periventricular leukomalacia, and some evidence that the use of postnatal steroids and non-use of antenatal steroids, were prognostic factors for CP. Male sex and gestational age were of limited use as prognostic factors for CP in cohorts restricted to ≤32 weeks gestation; however, in children older than 5 years with no major disability, there was evidence that male sex was a predictive factor for motor impairment. Interpretation This review has identified factors which may be of prognostic value for CP and motor impairment in VPT/VLBW children and will help to form the basis of future prognostic research." @default.
• W2273540556 created "2016-06-24" @default.
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• W2273540556 date "2016-02-10" @default.
• W2273540556 modified "2023-10-11" @default.
• W2273540556 title "Prognostic factors for cerebral palsy and motor impairment in children born very preterm or very low birthweight: a systematic review" @default.
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• W2273540556 doi "https://doi.org/10.1111/dmcn.12972" @default.
• W2273540556 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5321605" @default.
• W2273540556 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26862030" @default.
• W2273540556 hasPublicationYear "2016" @default.
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