Matches in SemOpenAlex for { <https://semopenalex.org/work/W2273663629> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2273663629 endingPage "1049" @default.
- W2273663629 startingPage "1044" @default.
- W2273663629 abstract "The effects of tumor necrosis factor (TNF) on hypoxic pulmonary vasoconstriction (HPV) and endothelium-dependent relaxation were examined in a blood-perfused rat lung preparation. Lungs from TNF-treated rats (0.26 mg/kg iv 12 h before experimentation) had a significantly greater HPV and a reduced vasorelaxant response to the endothelium-dependent vasodilator acetylcholine (ACh) but a similar vasorelaxant response to the endothelium-independent vasodilator nitroprusside compared with lungs from control rats (pretreated with 0.1 ml saline iv). Pentoxifylline (20 mg/kg iv and ip 20 min before administration of TNF) had no detectable effect on either HPV or ACh-induced relaxation but completely negated the augmentation on HPV and the inhibiting action on ACh-induced relaxation caused by TNF. The TNF effect on ACh relaxation was unaffected by pretreatment with L-arginine. These results indicate that TNF induces endothelial dysfunction and enhances HPV, effects that are inhibited by pentoxifylline." @default.
- W2273663629 created "2016-06-24" @default.
- W2273663629 creator A5027932130 @default.
- W2273663629 creator A5030258071 @default.
- W2273663629 creator A5042336210 @default.
- W2273663629 creator A5045717572 @default.
- W2273663629 creator A5084029368 @default.
- W2273663629 date "1992-03-01" @default.
- W2273663629 modified "2023-09-25" @default.
- W2273663629 title "Effect of tumor necrosis factor on hypoxic pulmonary vasoconstriction" @default.
- W2273663629 doi "https://doi.org/10.1152/jappl.1992.72.3.1044" @default.
- W2273663629 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1568958" @default.
- W2273663629 hasPublicationYear "1992" @default.
- W2273663629 type Work @default.
- W2273663629 sameAs 2273663629 @default.
- W2273663629 citedByCount "54" @default.
- W2273663629 countsByYear W22736636292012 @default.
- W2273663629 countsByYear W22736636292013 @default.
- W2273663629 countsByYear W22736636292014 @default.
- W2273663629 countsByYear W22736636292015 @default.
- W2273663629 countsByYear W22736636292016 @default.
- W2273663629 crossrefType "journal-article" @default.
- W2273663629 hasAuthorship W2273663629A5027932130 @default.
- W2273663629 hasAuthorship W2273663629A5030258071 @default.
- W2273663629 hasAuthorship W2273663629A5042336210 @default.
- W2273663629 hasAuthorship W2273663629A5045717572 @default.
- W2273663629 hasAuthorship W2273663629A5084029368 @default.
- W2273663629 hasConcept C120770815 @default.
- W2273663629 hasConcept C126322002 @default.
- W2273663629 hasConcept C134018914 @default.
- W2273663629 hasConcept C17991360 @default.
- W2273663629 hasConcept C185592680 @default.
- W2273663629 hasConcept C2775910092 @default.
- W2273663629 hasConcept C2776992346 @default.
- W2273663629 hasConcept C2777714996 @default.
- W2273663629 hasConcept C2779961880 @default.
- W2273663629 hasConcept C2780404050 @default.
- W2273663629 hasConcept C29323129 @default.
- W2273663629 hasConcept C42219234 @default.
- W2273663629 hasConcept C71924100 @default.
- W2273663629 hasConcept C98274493 @default.
- W2273663629 hasConceptScore W2273663629C120770815 @default.
- W2273663629 hasConceptScore W2273663629C126322002 @default.
- W2273663629 hasConceptScore W2273663629C134018914 @default.
- W2273663629 hasConceptScore W2273663629C17991360 @default.
- W2273663629 hasConceptScore W2273663629C185592680 @default.
- W2273663629 hasConceptScore W2273663629C2775910092 @default.
- W2273663629 hasConceptScore W2273663629C2776992346 @default.
- W2273663629 hasConceptScore W2273663629C2777714996 @default.
- W2273663629 hasConceptScore W2273663629C2779961880 @default.
- W2273663629 hasConceptScore W2273663629C2780404050 @default.
- W2273663629 hasConceptScore W2273663629C29323129 @default.
- W2273663629 hasConceptScore W2273663629C42219234 @default.
- W2273663629 hasConceptScore W2273663629C71924100 @default.
- W2273663629 hasConceptScore W2273663629C98274493 @default.
- W2273663629 hasIssue "3" @default.
- W2273663629 hasLocation W22736636291 @default.
- W2273663629 hasLocation W22736636292 @default.
- W2273663629 hasOpenAccess W2273663629 @default.
- W2273663629 hasPrimaryLocation W22736636291 @default.
- W2273663629 hasRelatedWork W1121880629 @default.
- W2273663629 hasRelatedWork W1984907427 @default.
- W2273663629 hasRelatedWork W1990263656 @default.
- W2273663629 hasRelatedWork W2159722818 @default.
- W2273663629 hasRelatedWork W2273663629 @default.
- W2273663629 hasRelatedWork W2389217615 @default.
- W2273663629 hasRelatedWork W2403070253 @default.
- W2273663629 hasRelatedWork W2416403798 @default.
- W2273663629 hasRelatedWork W3144611323 @default.
- W2273663629 hasRelatedWork W3176032424 @default.
- W2273663629 hasVolume "72" @default.
- W2273663629 isParatext "false" @default.
- W2273663629 isRetracted "false" @default.
- W2273663629 magId "2273663629" @default.
- W2273663629 workType "article" @default.