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- W2273753251 abstract "This editorial refers to ‘One in four major ischaemic disease events are fatal and 60% are pre-hospital deaths: a national data-linkage study’, by C. Grey et al ., doi:10.1093/eurheartj/ehv524.Coronary heart disease (CHD) mortality is declining in many European countries.1 This positive development is to a great extent due to decreasing levels of risk factors in the population.2 Despite the general increase in body weight and girth, slightly paradoxically, levels of blood pressure and serum cholesterol in the population are decreasing. This, in turn, is probably due to massive research aiming at detecting risk factors for CHD.With this in mind it is slightly surprising that CHD can be defined, and measured, in so many different ways. Common and important concepts in cardiovascular epidemiology such as incidence, prevalence, and mortality are difficult enough, but when it comes to anything that has to rely on a ratio between any two different numbers, comparing studies is quite a challenge.In measuring incidence, then, one has first to decide who is a case. Some studies, for instance the Multinational MONItoring of trends and determinants in CArdiovascular disease (MONICA), use very stringent criteria for acute myocardial infarction—by now, with the advent of highly sensitive markers of myocardial damage, very restrictive and limited to fairly severe cases.3 Unstable angina is usually not included but, while the rates of hospitalization for angina in Sweden essentially were reduced by two-thirds between 1998 and 2014 (from 374 to 126 per 100 000), the rates of acute myocardial infarction (AMI) decreased much less (from 274 to 209 per 100 000), probably reflecting much more changes in diagnostic practice and criteria for defining …" @default.
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- W2273753251 date "2015-11-18" @default.
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- W2273753251 title "Case fatality in coronary heart disease: the art of counting" @default.
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- W2273753251 doi "https://doi.org/10.1093/eurheartj/ehv613" @default.
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