FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2273806422> ?p ?o ?g. }

• W2273806422 endingPage "435" @default.
• W2273806422 startingPage "426" @default.
• W2273806422 abstract "Huntington's disease (HD) is a neurodegenerative disorder that produces a bias toward risky, reward-driven decisions in situations where the outcomes of decisions are uncertain and must be discovered. However, it is unclear whether HD patients show similar biases in decision-making when learning demands are minimized and prospective risks and outcomes are known explicitly. We investigated how risk decision-making strategies and adjustments are altered in HD patients when reward contingencies are explicit.HD (N=18) and healthy control (HC; N=17) participants completed a risk-taking task in which they made a series of independent choices between a low-risk/low reward and high-risk/high reward risk options.Computational modeling showed that compared to HC, who showed a clear preference for low-risk compared to high-risk decisions, the HD group valued high-risks more than low-risk decisions, especially when high-risks were rewarded. The strategy analysis indicated that when high-risk options were rewarded, HC adopted a conservative risk strategy on the next trial by preferring the low-risk option (i.e., they counted their blessings and then played the surer bet). In contrast, following a rewarded high-risk choice, HD patients showed a clear preference for repeating the high-risk choice.These results indicate a pattern of high-risk/high-reward decision bias in HD that persists when outcomes and risks are certain. The allure of high-risk/high-reward decisions in situations of risk certainty and uncertainty expands our insight into the dynamic decision-making deficits that create considerable clinical burden in HD." @default.
• W2273806422 created "2016-06-24" @default.
• W2273806422 creator A5000445228 @default.
• W2273806422 creator A5021370184 @default.
• W2273806422 creator A5028242243 @default.
• W2273806422 creator A5030317104 @default.
• W2273806422 creator A5052798133 @default.
• W2273806422 creator A5064135529 @default.
• W2273806422 creator A5064459907 @default.
• W2273806422 date "2015-12-28" @default.
• W2273806422 modified "2023-09-25" @default.
• W2273806422 title "The Allure of High-Risk Rewards in Huntington’s disease" @default.
• W2273806422 cites W1556630995 @default.
• W2273806422 cites W1847168837 @default.
• W2273806422 cites W1972090364 @default.
• W2273806422 cites W1975398216 @default.
• W2273806422 cites W1979892327 @default.
• W2273806422 cites W1981804286 @default.
• W2273806422 cites W1986235663 @default.
• W2273806422 cites W1987519006 @default.
• W2273806422 cites W1995119071 @default.
• W2273806422 cites W1996058957 @default.
• W2273806422 cites W1998152406 @default.
• W2273806422 cites W1998980185 @default.
• W2273806422 cites W2003919503 @default.
• W2273806422 cites W2005269174 @default.
• W2273806422 cites W2007304106 @default.
• W2273806422 cites W2007891770 @default.
• W2273806422 cites W2008854521 @default.
• W2273806422 cites W2010222763 @default.
• W2273806422 cites W2015770890 @default.
• W2273806422 cites W2023887533 @default.
• W2273806422 cites W2027361601 @default.
• W2273806422 cites W2027946127 @default.
• W2273806422 cites W2028298099 @default.
• W2273806422 cites W2031417185 @default.
• W2273806422 cites W2032147561 @default.
• W2273806422 cites W2034991875 @default.
• W2273806422 cites W2041479028 @default.
• W2273806422 cites W2048396168 @default.
• W2273806422 cites W2052047029 @default.
• W2273806422 cites W2058161128 @default.
• W2273806422 cites W2060588252 @default.
• W2273806422 cites W2060612339 @default.
• W2273806422 cites W2061116671 @default.
• W2273806422 cites W2067511615 @default.
• W2273806422 cites W2082056883 @default.
• W2273806422 cites W2089643759 @default.
• W2273806422 cites W2096452841 @default.
• W2273806422 cites W2102068574 @default.
• W2273806422 cites W2105402392 @default.
• W2273806422 cites W2105608590 @default.
• W2273806422 cites W2109360055 @default.
• W2273806422 cites W2118017277 @default.
• W2273806422 cites W2131675069 @default.
• W2273806422 cites W2148080316 @default.
• W2273806422 cites W2154017217 @default.
• W2273806422 cites W2162844379 @default.
• W2273806422 cites W2163647009 @default.
• W2273806422 cites W2165368112 @default.
• W2273806422 cites W2167311298 @default.
• W2273806422 cites W2168583567 @default.
• W2273806422 cites W2606710341 @default.
• W2273806422 cites W4206144694 @default.
• W2273806422 cites W4230546111 @default.
• W2273806422 cites W4241263290 @default.
• W2273806422 doi "https://doi.org/10.1017/s1355617715001241" @default.
• W2273806422 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5381648" @default.
• W2273806422 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26708084" @default.
• W2273806422 hasPublicationYear "2015" @default.
• W2273806422 type Work @default.
• W2273806422 sameAs 2273806422 @default.
• W2273806422 citedByCount "7" @default.
• W2273806422 countsByYear W22738064222017 @default.
• W2273806422 countsByYear W22738064222019 @default.
• W2273806422 countsByYear W22738064222020 @default.
• W2273806422 countsByYear W22738064222021 @default.
• W2273806422 countsByYear W22738064222022 @default.
• W2273806422 countsByYear W22738064222023 @default.
• W2273806422 crossrefType "journal-article" @default.
• W2273806422 hasAuthorship W2273806422A5000445228 @default.
• W2273806422 hasAuthorship W2273806422A5021370184 @default.
• W2273806422 hasAuthorship W2273806422A5028242243 @default.
• W2273806422 hasAuthorship W2273806422A5030317104 @default.
• W2273806422 hasAuthorship W2273806422A5052798133 @default.
• W2273806422 hasAuthorship W2273806422A5064135529 @default.
• W2273806422 hasAuthorship W2273806422A5064459907 @default.
• W2273806422 hasBestOaLocation W22738064222 @default.
• W2273806422 hasConcept C111472728 @default.
• W2273806422 hasConcept C126322002 @default.
• W2273806422 hasConcept C138885662 @default.
• W2273806422 hasConcept C15744967 @default.
• W2273806422 hasConcept C162118730 @default.
• W2273806422 hasConcept C162324750 @default.
• W2273806422 hasConcept C175444787 @default.
• W2273806422 hasConcept C180747234 @default.
• W2273806422 hasConcept C2779134260 @default.
• W2273806422 hasConcept C2779871187 @default.

• next