FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2274245557> ?p ?o ?g. }

• W2274245557 endingPage "247" @default.
• W2274245557 startingPage "239" @default.
• W2274245557 abstract "A selective barrier formed by intrinsically disordered Phe-Gly (FG) nucleoporins (Nups) allows transport receptor (TR)-facilitated translocation of signal-dependent cargos through the nuclear pore complexes (NPCs) of eukaryotic cells. However, the configuration of the FG-Nup barrier and its interactions with multiple TRs in native NPCs remain obscure. Here, we mapped the interaction sites of various TRs or FG segments within the FG-Nup barrier by using high-speed super-resolution microscopy and used these sites to reconstruct the three-dimensional tomography of the native barrier in the NPC. We found that each TR possesses a unique interaction zone within the FG-Nup barrier and that two major TRs, importin β1 and Crm1, outcompete other TRs in binding FG Nups. Moreover, TRs may alter the tomography of the FG-Nup barrier and affect one another's pathways under circumstances of heavy competition." @default.
• W2274245557 created "2016-06-24" @default.
• W2274245557 creator A5012369659 @default.
• W2274245557 creator A5023657528 @default.
• W2274245557 creator A5074838630 @default.
• W2274245557 date "2016-02-15" @default.
• W2274245557 modified "2023-10-11" @default.
• W2274245557 title "Super-resolution 3D tomography of interactions and competition in the nuclear pore complex" @default.
• W2274245557 cites W1519594915 @default.
• W2274245557 cites W1872971604 @default.
• W2274245557 cites W1965826457 @default.
• W2274245557 cites W1968975193 @default.
• W2274245557 cites W1980424624 @default.
• W2274245557 cites W2000440662 @default.
• W2274245557 cites W2003387590 @default.
• W2274245557 cites W2012077790 @default.
• W2274245557 cites W2014184000 @default.
• W2274245557 cites W2020951951 @default.
• W2274245557 cites W2022506021 @default.
• W2274245557 cites W2031620243 @default.
• W2274245557 cites W2038720967 @default.
• W2274245557 cites W2048492672 @default.
• W2274245557 cites W2052390654 @default.
• W2274245557 cites W2058041522 @default.
• W2274245557 cites W2058681782 @default.
• W2274245557 cites W2060318688 @default.
• W2274245557 cites W2061040254 @default.
• W2274245557 cites W2061637725 @default.
• W2274245557 cites W2070353646 @default.
• W2274245557 cites W2073526608 @default.
• W2274245557 cites W2076870182 @default.
• W2274245557 cites W2084711835 @default.
• W2274245557 cites W2088848543 @default.
• W2274245557 cites W2105987719 @default.
• W2274245557 cites W2117037202 @default.
• W2274245557 cites W2129821375 @default.
• W2274245557 cites W2133201628 @default.
• W2274245557 cites W2134814048 @default.
• W2274245557 cites W2140788063 @default.
• W2274245557 cites W2144781426 @default.
• W2274245557 cites W2145878324 @default.
• W2274245557 cites W2150359450 @default.
• W2274245557 cites W2153504753 @default.
• W2274245557 cites W2154883764 @default.
• W2274245557 cites W2155287673 @default.
• W2274245557 cites W2156328409 @default.
• W2274245557 cites W2157408408 @default.
• W2274245557 cites W2158446517 @default.
• W2274245557 cites W2158869723 @default.
• W2274245557 cites W2159923856 @default.
• W2274245557 cites W2162175822 @default.
• W2274245557 cites W2166034073 @default.
• W2274245557 cites W2171940778 @default.
• W2274245557 cites W4251721708 @default.
• W2274245557 doi "https://doi.org/10.1038/nsmb.3174" @default.
• W2274245557 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5922253" @default.
• W2274245557 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26878241" @default.
• W2274245557 hasPublicationYear "2016" @default.
• W2274245557 type Work @default.
• W2274245557 sameAs 2274245557 @default.
• W2274245557 citedByCount "53" @default.
• W2274245557 countsByYear W22742455572016 @default.
• W2274245557 countsByYear W22742455572017 @default.
• W2274245557 countsByYear W22742455572018 @default.
• W2274245557 countsByYear W22742455572019 @default.
• W2274245557 countsByYear W22742455572020 @default.
• W2274245557 countsByYear W22742455572021 @default.
• W2274245557 countsByYear W22742455572022 @default.
• W2274245557 countsByYear W22742455572023 @default.
• W2274245557 crossrefType "journal-article" @default.
• W2274245557 hasAuthorship W2274245557A5012369659 @default.
• W2274245557 hasAuthorship W2274245557A5023657528 @default.
• W2274245557 hasAuthorship W2274245557A5074838630 @default.
• W2274245557 hasBestOaLocation W22742455572 @default.
• W2274245557 hasConcept C12554922 @default.
• W2274245557 hasConcept C126725582 @default.
• W2274245557 hasConcept C133882971 @default.
• W2274245557 hasConcept C185592680 @default.
• W2274245557 hasConcept C2780114586 @default.
• W2274245557 hasConcept C2780723820 @default.
• W2274245557 hasConcept C59157529 @default.
• W2274245557 hasConcept C68556195 @default.
• W2274245557 hasConcept C86803240 @default.
• W2274245557 hasConcept C95444343 @default.
• W2274245557 hasConceptScore W2274245557C12554922 @default.
• W2274245557 hasConceptScore W2274245557C126725582 @default.
• W2274245557 hasConceptScore W2274245557C133882971 @default.
• W2274245557 hasConceptScore W2274245557C185592680 @default.
• W2274245557 hasConceptScore W2274245557C2780114586 @default.
• W2274245557 hasConceptScore W2274245557C2780723820 @default.
• W2274245557 hasConceptScore W2274245557C59157529 @default.
• W2274245557 hasConceptScore W2274245557C68556195 @default.
• W2274245557 hasConceptScore W2274245557C86803240 @default.
• W2274245557 hasConceptScore W2274245557C95444343 @default.
• W2274245557 hasIssue "3" @default.
• W2274245557 hasLocation W22742455571 @default.
• W2274245557 hasLocation W22742455572 @default.
• W2274245557 hasLocation W22742455573 @default.

• next