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- W2274292332 abstract "BACKGROUND: It is well known that the quality of life (QoL) of patients with chronic kidney disease (CKD) can be improved by initiation of dialysis. The purpose of this study is to investigate the association between dialysis adequacy, comorbidity indices, and QoL domains in a cohort of incident peritoneal dialysis (PD) patients.METHODS: This was a prospective 6-month observational study. Seventy-seven incident PD patients who were treated in a hospital-facilitated PD center for 6 consecutive months were enrolled. The mean patient age was 47.3 ± 13.4 years, and 38 patients were male. The effects of baseline PD adequacy indices, Charlson comorbidity index (CCI) on QoL were investigated in a 6-month period. The Short-form- 36 (SF-36) health survey questionnaire was employed to assess the QoL of the patients. The outcomes were measured as changes in scores of the various domains of SF-36 after the 6-month PD therapy. Multivariate analysis was performed to assess the effects of the abovementioned indices on QoL.RESULTS: The cutoff level of 1.2 for baseline peritoneal Kt/V urea level was found to have the greatest effect on scores of the SF-36 domains after the 6-month PD period. Patients with baseline peritoneal Kt/V urea levels of ≥ 1.2 had improvement in the components of general health, physical functioning, role limitation caused by physical problems, and bodily pain. However, patients with baseline peritoneal Kt/V urea level of ＜ 1.2 had improvement only in components of physical functioning and role limitation due to physical problems. Multivariate analysis revealed that a CCI score of ≥ 5 did not have any significant influence in any of the SF-36 domains, while CCI scores of 3-5 were associated with an improvement in the domains of role limitation due to physical problems (P=0.001) and role limitation due to emotional problems (P=0.025).CONCLUSIONS: The baseline level of peritoneal Kt/V urea correlates significantly with the scores of various components of QoL after PD initiation. PD patients with moderate comorbidities had significant improvement in QoL when PD was initiated." @default.
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- W2274292332 date "2013-09-01" @default.
- W2274292332 modified "2023-10-18" @default.
- W2274292332 title "Relationship between Kt/V Urea Values, Comorbidity Index and Components of Quality of Life in Incident Peritoneal Dialysis Patients" @default.
- W2274292332 doi "https://doi.org/10.6221/an.2012034" @default.
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