Matches in SemOpenAlex for { <https://semopenalex.org/work/W2274460091> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2274460091 endingPage "61" @default.
- W2274460091 startingPage "258" @default.
- W2274460091 abstract "FLT3 ITD and D835 mutations occur in high frequency in AML and to a lower rate in ALL patients with poor prognosis.ITD and D835 mutations were studied in 100 diagnosed acute leukemia patients including 27 AML and 73 ALL with various FAB classifications by PCR and PCR-RFLP, respectively. Subsequently, PCR products of positive samples were confirmed by sequencing analyses.ITD mutations occurred in 10% of all pediatric acute leukemia, including AML and ALL. 25.9% of AML patients harbor a mutation in the ITD in various subtypes. The frequency of ITD mutations was 4% in ALL. Various insertions of nucleotides in ITD were observed, similar to those described in the literature previously.These preliminary data suggest that flt3-ITD mutations may play an important role in leukemogenesis in a proportion of children, particularly in the case of AML." @default.
- W2274460091 created "2016-06-24" @default.
- W2274460091 creator A5022063041 @default.
- W2274460091 creator A5051104732 @default.
- W2274460091 creator A5051993360 @default.
- W2274460091 creator A5058047169 @default.
- W2274460091 creator A5079394547 @default.
- W2274460091 creator A5083088838 @default.
- W2274460091 date "2014-04-01" @default.
- W2274460091 modified "2023-09-25" @default.
- W2274460091 title "Detection and biological characteristic of FLT3 gene mutations in children with acute leukemia." @default.
- W2274460091 cites W1542395305 @default.
- W2274460091 cites W1968306285 @default.
- W2274460091 cites W1971028883 @default.
- W2274460091 cites W1977802046 @default.
- W2274460091 cites W1984578995 @default.
- W2274460091 cites W1989402731 @default.
- W2274460091 cites W2004477791 @default.
- W2274460091 cites W2008738614 @default.
- W2274460091 cites W2034820298 @default.
- W2274460091 cites W2040950977 @default.
- W2274460091 cites W2069057374 @default.
- W2274460091 cites W2076436122 @default.
- W2274460091 cites W2093423704 @default.
- W2274460091 cites W2105098863 @default.
- W2274460091 cites W2110632922 @default.
- W2274460091 cites W2130864403 @default.
- W2274460091 cites W2131557977 @default.
- W2274460091 cites W2151060192 @default.
- W2274460091 cites W2154987486 @default.
- W2274460091 cites W2298073652 @default.
- W2274460091 cites W2317475893 @default.
- W2274460091 cites W2321946412 @default.
- W2274460091 cites W2407963460 @default.
- W2274460091 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24724602" @default.
- W2274460091 hasPublicationYear "2014" @default.
- W2274460091 type Work @default.
- W2274460091 sameAs 2274460091 @default.
- W2274460091 citedByCount "2" @default.
- W2274460091 countsByYear W22744600912020 @default.
- W2274460091 countsByYear W22744600912022 @default.
- W2274460091 crossrefType "journal-article" @default.
- W2274460091 hasAuthorship W2274460091A5022063041 @default.
- W2274460091 hasAuthorship W2274460091A5051104732 @default.
- W2274460091 hasAuthorship W2274460091A5051993360 @default.
- W2274460091 hasAuthorship W2274460091A5058047169 @default.
- W2274460091 hasAuthorship W2274460091A5079394547 @default.
- W2274460091 hasAuthorship W2274460091A5083088838 @default.
- W2274460091 hasConcept C104317684 @default.
- W2274460091 hasConcept C126322002 @default.
- W2274460091 hasConcept C143998085 @default.
- W2274460091 hasConcept C2778461978 @default.
- W2274460091 hasConcept C49105822 @default.
- W2274460091 hasConcept C501734568 @default.
- W2274460091 hasConcept C502942594 @default.
- W2274460091 hasConcept C54355233 @default.
- W2274460091 hasConcept C71924100 @default.
- W2274460091 hasConcept C86803240 @default.
- W2274460091 hasConceptScore W2274460091C104317684 @default.
- W2274460091 hasConceptScore W2274460091C126322002 @default.
- W2274460091 hasConceptScore W2274460091C143998085 @default.
- W2274460091 hasConceptScore W2274460091C2778461978 @default.
- W2274460091 hasConceptScore W2274460091C49105822 @default.
- W2274460091 hasConceptScore W2274460091C501734568 @default.
- W2274460091 hasConceptScore W2274460091C502942594 @default.
- W2274460091 hasConceptScore W2274460091C54355233 @default.
- W2274460091 hasConceptScore W2274460091C71924100 @default.
- W2274460091 hasConceptScore W2274460091C86803240 @default.
- W2274460091 hasIssue "4" @default.
- W2274460091 hasLocation W22744600911 @default.
- W2274460091 hasOpenAccess W2274460091 @default.
- W2274460091 hasPrimaryLocation W22744600911 @default.
- W2274460091 hasRelatedWork W136468098 @default.
- W2274460091 hasRelatedWork W1562693820 @default.
- W2274460091 hasRelatedWork W1895018249 @default.
- W2274460091 hasRelatedWork W1984225124 @default.
- W2274460091 hasRelatedWork W2002595078 @default.
- W2274460091 hasRelatedWork W2016225921 @default.
- W2274460091 hasRelatedWork W2068588654 @default.
- W2274460091 hasRelatedWork W2109451199 @default.
- W2274460091 hasRelatedWork W2119462611 @default.
- W2274460091 hasRelatedWork W2135257384 @default.
- W2274460091 hasVolume "17" @default.
- W2274460091 isParatext "false" @default.
- W2274460091 isRetracted "false" @default.
- W2274460091 magId "2274460091" @default.
- W2274460091 workType "article" @default.