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• W2274532029 abstract "A new protocol for the diasteroselective synthesis of pyrrolidin-2-ones 4–14 is presented. Aquivion PFSA effectively catalyzed the diasteroselective nitro-mannich/lactamization cascade reaction between the imine formed from aldehydes 1a–g and amines 2a–b with methyl 3-nitropropanoate 3. The use of flow conditions allow a very efficient waste minimization confirmed by representative green metrics calculations." @default.
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• W2274532029 date "2015-07-07" @default.
• W2274532029 modified "2023-10-16" @default.
• W2274532029 title "Aquivion PFSA as a Novel Solid and Reusable Acid Catalyst in the Synthesis of 2-Pyrrolidin-2-ones in Flow" @default.
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• W2274532029 doi "https://doi.org/10.1021/acssuschemeng.5b00470" @default.
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