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- W2274541818 abstract "BackgroundAn efficient and reliable parameter estimation method is essential for the creation of biological models using ordinary differential equation (ODE). Most of the existing estimation methods involve finding the global minimum of data fitting residuals over the entire parameter space simultaneously. Unfortunately, the associated computational requirement often becomes prohibitively high due to the large number of parameters and the lack of complete parameter identifiability (i.e. not all parameters can be uniquely identified)." @default.
- W2274541818 created "2016-06-24" @default.
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- W2274541818 date "2012-11-01" @default.
- W2274541818 modified "2023-09-27" @default.
- W2274541818 title "Incremental parameter estimation of kinetic metabolic network models" @default.
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