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- W2274797655 abstract "ABSTRACT Using sequence homology to the Drosophila Antenna-pedia gene, we isolated a homeobox-containing gene from the lepidopteran, Manduca sexta. Sequence analysis and in situ hybridizations to tissue sections suggest that the Manduca gene encodes a lepidopteran homologue of the Drosophila Bithorax complex gene abdominal-A. The predicted amino acid sequence of a 76 amino acid region that includes the homeobox and the regions immediately flanking it are identical between the Manduca and Drosophila genes. Northern blots reveal that the Manduca abd-A gene is expressed first in the early embryo and continues to be expressed throughout later embryonic and larval stages. In situ hybridizations show that the posterior half of the first abdominal segment marks the anterior border of the Manduca abdA expression. This expression pattern demonstrates the conservation of parasegments as domains of gene activity in the lepidopteran embryo. The Manduca abd-A expression extends from the posterior half of the first abdominal segment through the tenth abdominal segment, a domain that is greater than that of the Drosophila abd-A expression, and reflects the difference in visible segment number between the two insects." @default.
- W2274797655 created "2016-06-24" @default.
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- W2274797655 date "1991-05-01" @default.
- W2274797655 modified "2023-09-25" @default.
- W2274797655 title "Isolation and embryonic expression of an <i>abdominal-A-like</i> gene from the lepidopteran, <i>Manduca sexta</i>" @default.
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- W2274797655 doi "https://doi.org/10.1242/dev.112.1.119" @default.
- W2274797655 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1685112" @default.
- W2274797655 hasPublicationYear "1991" @default.
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