FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2274852783> ?p ?o ?g. }

• W2274852783 endingPage "90" @default.
• W2274852783 startingPage "81" @default.
• W2274852783 abstract "Since the introduction of on-line substituate preparation, high substituate rates (Q s ) in pre- and postdilution for hemodiafiltration (HDF) procedures can be realized. During postdilution HDF (POD-HDF) and additional convective removal is possible, but in vivo Q s is limited to approx. 1/3Q b (bloodflow). With predilution HDF (PRD-HDF) higher Q s and therefore high convective transport rates by ultrafiltration can be reached. On the other hand the blood concentration is diminished by predilution. Further decrease of the diffusive transport is caused by reduced dialysate flow Q d due to separation of the substituate from the dialysate (Fresenius 4008 On-Line HDF, Gambro AK100 Ultra). The theoretical description of the combined diffusive-convective transport is limited to 1-dimensional models and small UF-rates. Therefore for practical and theoretical purposes the assessment of the efficacy of on-line PRD-HDF and POD-HDF in different molecular weight ranges is desirable. By means of in vitro experiments the effective clearances K eff of hemodialysis (HD, dialyzer: Fresenius F60) for urea, creatinine, vitamin B12 and inulin were compared with measured and theoretical K eff of POD- and PRD-HDF. The theoretical expectation is confirmed that K eff for small molecular weight substances decreases slightly with PRD-HDF and increases for larger molecules. In the case of POD-HDF K eff for small molecular weight substances increases slightly and strongly for larger molecules. In vivo experiments were performed to measure the real substance removal from patient's blood and to figure out the impact of dialysate flow (collection of the used dialysate during the 1. treatment hour and concentration measurements for urea, creatinine, phosphate, ß 2 -MG). The results show that the substraction of Q s from Q d reduces K eff for urea, creatinine and phosphate but not for ß 2 -MG. PRD-HDF with Q d = 500 ml/min is significantly less effective for small molecules than HD. There is no significant difference of K eff for urea, creatinine, phosphate during HD and PRD-HDF with Q d = 800 ml/min, but a significant increase of 10-15% for POD-HDF K eff for ß 2 -MG increases by 75% for PRD-HDF and 95% for POD-HDF compared with HD (Q d = 500 ml/min)." @default.
• W2274852783 created "2016-06-24" @default.
• W2274852783 creator A5011761816 @default.
• W2274852783 creator A5020336170 @default.
• W2274852783 creator A5027234777 @default.
• W2274852783 creator A5061721799 @default.
• W2274852783 creator A5066135428 @default.
• W2274852783 date "1997-02-01" @default.
• W2274852783 modified "2023-09-30" @default.
• W2274852783 title "On-Line Hemodiafiltration with Pre- and Postdilution: A Comparison of Efficacy" @default.
• W2274852783 cites W117412121 @default.
• W2274852783 cites W1968491914 @default.
• W2274852783 cites W1973664860 @default.
• W2274852783 cites W1977975161 @default.
• W2274852783 cites W1998488617 @default.
• W2274852783 cites W2051352388 @default.
• W2274852783 cites W2061079390 @default.
• W2274852783 cites W2076585809 @default.
• W2274852783 cites W2078491742 @default.
• W2274852783 cites W2278787296 @default.
• W2274852783 cites W2417777158 @default.
• W2274852783 cites W4245985860 @default.
• W2274852783 doi "https://doi.org/10.1177/039139889702000206" @default.
• W2274852783 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9093885" @default.
• W2274852783 hasPublicationYear "1997" @default.
• W2274852783 type Work @default.
• W2274852783 sameAs 2274852783 @default.
• W2274852783 citedByCount "58" @default.
• W2274852783 countsByYear W22748527832012 @default.
• W2274852783 countsByYear W22748527832013 @default.
• W2274852783 countsByYear W22748527832015 @default.
• W2274852783 countsByYear W22748527832017 @default.
• W2274852783 countsByYear W22748527832018 @default.
• W2274852783 countsByYear W22748527832021 @default.
• W2274852783 countsByYear W22748527832022 @default.
• W2274852783 crossrefType "journal-article" @default.
• W2274852783 hasAuthorship W2274852783A5011761816 @default.
• W2274852783 hasAuthorship W2274852783A5020336170 @default.
• W2274852783 hasAuthorship W2274852783A5027234777 @default.
• W2274852783 hasAuthorship W2274852783A5061721799 @default.
• W2274852783 hasAuthorship W2274852783A5066135428 @default.
• W2274852783 hasConcept C137776501 @default.
• W2274852783 hasConcept C185592680 @default.
• W2274852783 hasConcept C43617362 @default.
• W2274852783 hasConcept C50817676 @default.
• W2274852783 hasConcept C6557445 @default.
• W2274852783 hasConcept C86803240 @default.
• W2274852783 hasConceptScore W2274852783C137776501 @default.
• W2274852783 hasConceptScore W2274852783C185592680 @default.
• W2274852783 hasConceptScore W2274852783C43617362 @default.
• W2274852783 hasConceptScore W2274852783C50817676 @default.
• W2274852783 hasConceptScore W2274852783C6557445 @default.
• W2274852783 hasConceptScore W2274852783C86803240 @default.
• W2274852783 hasIssue "2" @default.
• W2274852783 hasLocation W22748527831 @default.
• W2274852783 hasLocation W22748527832 @default.
• W2274852783 hasOpenAccess W2274852783 @default.
• W2274852783 hasPrimaryLocation W22748527831 @default.
• W2274852783 hasRelatedWork W1970910281 @default.
• W2274852783 hasRelatedWork W1994033534 @default.
• W2274852783 hasRelatedWork W1997079253 @default.
• W2274852783 hasRelatedWork W2000793212 @default.
• W2274852783 hasRelatedWork W2003656025 @default.
• W2274852783 hasRelatedWork W2034256531 @default.
• W2274852783 hasRelatedWork W2069842851 @default.
• W2274852783 hasRelatedWork W2091822078 @default.
• W2274852783 hasRelatedWork W2170848977 @default.
• W2274852783 hasRelatedWork W2973634502 @default.
• W2274852783 hasVolume "20" @default.
• W2274852783 isParatext "false" @default.
• W2274852783 isRetracted "false" @default.
• W2274852783 magId "2274852783" @default.
• W2274852783 workType "article" @default.