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- W2275031644 abstract "The reported high correlation between exposure in utero to diethylstilbestrol (DES) and delayed development of vaginal cancer in young women is discussed as the 1st reported incident of transplacental carcinogenesis in humans. The author touts 3 main points: 1) physicians must not administer drugs the long-term effects of which are unknown; 2) physicians must recognize that irregular menses and heavy vaginal bleeding in young women must not be dismissed as anovulatory cycles without a careful vaginal examination; and 3) physicians must remember that though to date DES-associated mutagenesis has occurred only in women male offspring may also be affected so national surveillance centers must be readied." @default.
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- W2275031644 date "1972-06-01" @default.
- W2275031644 modified "2023-09-23" @default.
- W2275031644 title "Female genital tract carcinoma and maternal stilbesterol." @default.
- W2275031644 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/5033066" @default.
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