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• W2275304853 abstract "The first enantioselective Friedel–Crafts alkylation of indoles and pyrroles with 3-hydroxy-3-indolyloxindoles to access two novel types of 3,3-diaryloxindoles catalyzed by chiral imidodiphosphoric acids has been reported. A range of quaternary carbon centered 3,3-diaryloxindoles were synthesized in high yield (up to >99%) with excellent enantioselectivity (up to 98% ee) at low catalyst loadings (as low as 0.5 mol%). The Friedel–Crafts reaction between indoles and 3-hydroxy-3-indolyloxindoles is amenable to gram scale syntheses." @default.
• W2275304853 created "2016-06-24" @default.
• W2275304853 creator A5007136153 @default.
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• W2275304853 creator A5074815521 @default.
• W2275304853 date "2016-02-17" @default.
• W2275304853 modified "2023-10-08" @default.
• W2275304853 title "Chiral Imidodiphosphoric Acids-Catalyzed Friedel-Crafts Reactions of Indoles/Pyrroles with 3-Hydroxy-indolyloxindoles: Enantioselective Synthesis of 3,3-Diaryloxindoles" @default.
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• W2275304853 doi "https://doi.org/10.1002/adsc.201500985" @default.
• W2275304853 hasPublicationYear "2016" @default.
• W2275304853 type Work @default.
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