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- W227546229 abstract "Abstract : This research resulted in the design and synthesis of new nanoconjugates with the ability to target multidrug resistant tumors. Additionally, the work has helped to initiate a new research program focused on the delivery of drugs to the brain. Both tracks of research are continuing in the PI s laboratory. Most surprisingly, we discovered that a simple P-gp substrate that has no other pharmacological effects, is easily conjugated to the delivery system and effectively targets MDR cells. This is particularly exciting because for drug targeting to the brain, having minimal off-target pharmacological activity is important toward the development of an effective delivery vehicle (i.e., low side effects)." @default.
- W227546229 created "2016-06-24" @default.
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- W227546229 date "2011-10-01" @default.
- W227546229 modified "2023-09-23" @default.
- W227546229 title "Exploitation of P-glycoprotein Over-expression for Targeted Drug Delivery to Breast Cancer" @default.
- W227546229 doi "https://doi.org/10.21236/ada571769" @default.
- W227546229 hasPublicationYear "2011" @default.
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