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• W2275617560 abstract "<p>ABSTRACT</p><p>PURPOSE: Quantify and localize lenticular forward scatter using Shack-Hartmann wavefront sensing (SHWS) as single-valued metrics and a scatter map, and to examine the relationships between forward scatter and backscatter metrics and visual acuity.</p><p>METHODS: We obtained SHWS images from 148 patients in the Texas Investigation of Cataract Optics study. Patient age was 22 to 84 years, with Lens Opacities Classification System III (LOCS III) nuclear opalescence (NO) scores ranging from 0.8 to 5.6. Visual acuities were measured at photopic (280 cd/m^{p 2}) high (VA^sub PHC^) and low contrast (VA^sub PLC^) and mesopic (0.75 cd/m^{p 2}) high (VA^sub MHC^) and low contrast (VA^sub MLC^). Scattering was described in a scatter map and by five single-valued metrics characterizing SHWS lens let point spread functions. The relationships between scatter and visual acuity were tested using linear regression.</p><p>RESULTS: Visual acuities decreased proportional to both LOCS III NO (R^{p 2}=up to 39%) and scatter metrics (R^{p 2}=up to 21%). Stepwise multiple linear regression improved visual acuity prediction by including a backscatter and a forward scatter metric (R^{p 2} up to 51.2%). For the subjects over age 60 years (N=46, 68.8?6.12 years), the forward scatter metrics explain as much variance in visual acuities (R^{p 2}=up to 29%) as LOCS III NO (R^{p 2}=up to 26%). Combined they accounted for up to 48.8% of visual acuity variance.</p><p>CONCLUSION: Forward light scatter can be quantified using SHWS and the resulting metrics explain significant variance in visual acuity, especially in the aging eye. Together with a backscatter metric they explain approximately 50% of the variance in VA. [J Refract Surg 2004;20:S515-S522]</p>" @default.
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• W2275617560 date "2004-09-03" @default.
• W2275617560 modified "2023-09-23" @default.
• W2275617560 title "Quantifying Scatter in Shack-Hartmann Images to Evaluate Nuclear Cataract" @default.
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• W2275617560 doi "https://doi.org/10.3928/1081-597x-20040901-21" @default.
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