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- W2275694884 abstract "Purpose: Synovial fluid (SF) leptin has been shown to have an association with cartilage degeneration. Our objective was to examine the relationship between different measures of body habitus and SF leptin levels in an end stage knee osteoarthritis (OA) population. Method: Sixty consecutive patients with knee OA were surveyed prior to surgery for demographic data. Body habitus was assessed with the body mass index (BMI), waist circumference (WC) and waist-hip ratio (WHR). SF and serum samples were analyzed for leptin and adiponectin using specific ELISA. Non-parametric correlations and linear regression modeling was used to identify the relationship between the measures of body habitus and SF leptin levels. Results: Females had greater levels of leptin than males in both the serum and SF. Significant correlations were found between SF leptin levels and BMI and WC (R2 0.44 and 0.38 respectively, p Conclusion: WC may be a more accurate measure of body habitus than BMI in the relationship between the metabolic effects of adipose tissue and OA." @default.
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- W2275694884 date "2011-07-01" @default.
- W2275694884 modified "2023-09-24" @default.
- W2275694884 title "90. THE RELATIONSHIP BETWEEN BODY HABITUS AND LEPTIN IN A KNEE OSTEOARTHRITIS POPULATION" @default.
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