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- W2275988894 abstract "Objective: The aim of this experimental study was to examine the effect of the antioxidant drug U-74389G in a rat model of hypoxia reoxygenation using the previously established protocol. Effects of treatments were evaluated by magnesium (Mg2+) levels in blood.
 Methods: Nonrandomized controlled study was performed. Mg2+ levels were determined in 60 min (groups A and C) and 120 min (groups B and D) after starting the reoxygenation. Groups A and B received no drugs, whereas rats from groups C and D were administered with U-74389G.
 Results: 40 rats 1618 weeks old of a mean weight of 2312 g were employed in the study. It is demonstrated that U-74389G administration did not alter the Mg2+ levels (decrease in Mg2+ concentration was 0.282.75%; p =0.917). Reoxygenation non-significantly increased the Mg2+ levels by 4.272.66% (p =0.107). Together, the U-74389G administration and reoxygenation non-significantly increased the Mg2+ levels by 0.361.64% (p =0.823).
 Conclusion: U-74389G administration, alone or in concert with reoxygenation did not significantly affect Mg2+ level in blood after experimental hypoxia in rats." @default.
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- W2275988894 date "2015-09-28" @default.
- W2275988894 modified "2023-09-26" @default.
- W2275988894 title "The Effect of the Antioxidant Drug U-74389G on Magnesium Levels During Hypoxia–Reoxygenation Injury in Rats" @default.
- W2275988894 doi "https://doi.org/10.15690/vramn.v70.i4.1405" @default.
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