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- W2276149713 abstract "The main conclusion of this study is that a profound suppression of the pituitary and ovary can be associated with an inadequate response which may require a longer or different regimen of stimulation to achieve the desired outcome for IVF. We suggest that a pretreatment determination of E2 and gonadotropins can be of value to predict the nature of ovarian response in women with suppressed pituitary-ovarian function.A profound suppression of the pituitary and the ovary is connected to an inadequate response to gonadotropin therapy. The therapy, used to produce multiple follicular development for in vitro fertilization (IVF), can cause a variety of responses including: premature luteinization, inadequate amount of preovulatory follicles and an asynchrony of follicular maturation. The aforementioned responses are related to lowered IVF success. IVF patients who received oral contraceptives as part of treatment had undesirable responses to human menopausal gonadotropin when the contraceptives were administered for only a short period. It is suggested that a different regimen be pursued to achieve adequate responses. A pretreatment determination of E and gonadotropins is a viable method of predicting ovarian response among women who have suppressed pituitary-ovarian function. It is further concluded that a favorable response to hMG was not found in IVF patients when treatments of oral contraceptives are administered for a short period." @default.
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- W2276149713 date "1988-09-01" @default.
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- W2276149713 title "Ovarian response to human menopausal gonadotropin following suppression with oral contraceptives" @default.
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- W2276149713 doi "https://doi.org/10.1016/s0015-0282(16)60144-9" @default.
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