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- W2276240424 abstract "Osteoporosis (ie, low bone mineral density) is common in ankylosing spondylitis, related to both systemic inflammation and decreased mobility. Vertebral fracture risk is increased; acute back pain in these patients is not always a flare-up of the disease, as it can be related to bone complications. Intervertebral disc fractures in the ankylosed spine are associated with severe neurological complications. As expected from pathophysiology, treatments effective against inflammation have a positive effect on bone, and prospective open studies have shown that tumour-necrosis-factor blockers can improve bone mineral density at the spine and the hip. There is so far no evidence of a decreased risk of fractures with such treatment." @default.
- W2276240424 created "2016-06-24" @default.
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- W2276240424 date "2015-07-01" @default.
- W2276240424 modified "2023-10-04" @default.
- W2276240424 title "Inflammation, bone loss and fracture risk in spondyloarthritis: Figure 1" @default.
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- W2276240424 doi "https://doi.org/10.1136/rmdopen-2015-000052" @default.
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