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- W2276447880 abstract "To observe the immunomodulating effect of formulation of Fufang Jianwei Xiaoshi in mice, 80 healthy female BALB/C mice (6～ 8 weeks old) were administered with formulation of Fufang Jian Wwei Xiaoshi for 30 days with the dose of 0, 0.2, 0.6 and 1.8g/kgBW (body weight), then the capacity of spleen T lymphocyte proliferation, delayed allergic reaction (DTH), the number of plaque-forming cells, the level of serum HC50 and natural killer cell activity were determined. In comparison with the values of the control group, the administration of Fufang Jianwei Xiaoshi of 0.6g/kgBW can significantly raise the capacity of the mitogen Concanavalin A (Con A)-induced lymphocyte proliferation, the administration of 1.8g/kgBW sees no significant effect, with only a slight increase. The administration of 0.6g/kgBW and 1.8g/kgBW of Fufang Jianwei Xiaoshi can enhance the delayed allergic reaction (DTH); all groups of Jianwei Xiaoshi see an increase of the number of plaque-forming cells; the administration of 0.6g/kgBW and 1.8g/kgBW of Fufang Jianwei Xiaoshi can increase the cell activity of the natural killer. Nevertheless, no significant differences on the level of serum HC50 between control group and administration groups were observed in our study. These results suggest that the formulation of Fufang Jianwei Xiaoshi is a possible immune stimulant and may strengthen the immune function on cellular immunity, the humoral immunity and the cell activity of the natural killer." @default.
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- W2276447880 date "2010-01-01" @default.
- W2276447880 modified "2023-09-24" @default.
- W2276447880 title "Experimental study on immunomodulating effect of formulation of Fufang Jianwei Xiaoshi." @default.
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