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• W2276526054 abstract "Approximately 80% of prostate cancers exhibit some degree of bone metastasis. The role of the bone marrow and the hematopoietic stem cell (HSC) niche in attracting metastatic cells and maintaining dormancy of disseminated tumor cells (DTCs) is an increasingly important topic towards the development of novel prostate cancer therapies. This paper reviews aspects of the HSC niche that lead to prostate cancer cell homing and dormancy in the bone marrow. This review also discusses the role of DTCs in the niche environment and discusses the role of erythropoietin in targeting DTCs within the HSC niche." @default.
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• W2276526054 date "2016-09-01" @default.
• W2276526054 modified "2023-10-17" @default.
• W2276526054 title "The role of hematopoietic stem cell niche in prostate cancer bone metastasis" @default.
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• W2276526054 doi "https://doi.org/10.1016/j.jbo.2016.02.005" @default.
• W2276526054 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5063229" @default.
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