FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2276536049> ?p ?o ?g. }

• W2276536049 abstract "The fitness of somatic cells of metazoan, the ability of proliferation and survival, depends on microenvironment. In somatic evolution, a mutated cell in a tissue clonally expands abnormally because of its high fitness as normal cells in a corresponding microenvironment. In this study, we propose the cancer cell hypothesis that cancer cells are the mutated cells with two characteristics: clonal expansion and damaging the microenvironment through the behaviours such as producing more poison in metabolism than normal cells. This model provides an explanation for the nature of invasion and metastasis, which are still controversial. In addition, we theoretically reasoned out that normal cells have almost the highest fitness in healthy microenvironments as a result of long-term organic evolution. This inspires a new kind of therapy of cancer, which improving microenvironment to make cancer cells lower in fitness than normal cells and then halt the growth of tumours. This general therapy relies on a mechanism differing from chemotherapy and targeted therapy." @default.
• W2276536049 created "2016-06-24" @default.
• W2276536049 creator A5030636719 @default.
• W2276536049 creator A5083369904 @default.
• W2276536049 date "2014-05-06" @default.
• W2276536049 modified "2023-09-22" @default.
• W2276536049 title "Recognizing Cancer via Somatic and Organic Evolution" @default.
• W2276536049 cites W1494567425 @default.
• W2276536049 cites W1497663772 @default.
• W2276536049 cites W173436758 @default.
• W2276536049 cites W1835750525 @default.
• W2276536049 cites W1912673154 @default.
• W2276536049 cites W1964081206 @default.
• W2276536049 cites W1974511120 @default.
• W2276536049 cites W1979988883 @default.
• W2276536049 cites W1980847511 @default.
• W2276536049 cites W1993875664 @default.
• W2276536049 cites W1998728654 @default.
• W2276536049 cites W2005334224 @default.
• W2276536049 cites W2023204024 @default.
• W2276536049 cites W2023560061 @default.
• W2276536049 cites W2034269086 @default.
• W2276536049 cites W2040190138 @default.
• W2276536049 cites W2042198997 @default.
• W2276536049 cites W2045582876 @default.
• W2276536049 cites W2058648826 @default.
• W2276536049 cites W2062210712 @default.
• W2276536049 cites W2062265555 @default.
• W2276536049 cites W2062809449 @default.
• W2276536049 cites W2066861312 @default.
• W2276536049 cites W2067507447 @default.
• W2276536049 cites W2072928176 @default.
• W2276536049 cites W2073006184 @default.
• W2276536049 cites W2080264320 @default.
• W2276536049 cites W2080726412 @default.
• W2276536049 cites W2091723114 @default.
• W2276536049 cites W2095510701 @default.
• W2276536049 cites W2099802436 @default.
• W2276536049 cites W2105241495 @default.
• W2276536049 cites W2107268345 @default.
• W2276536049 cites W2117692326 @default.
• W2276536049 cites W2137449168 @default.
• W2276536049 cites W2145139438 @default.
• W2276536049 cites W2147328441 @default.
• W2276536049 cites W2162290846 @default.
• W2276536049 cites W2170349147 @default.
• W2276536049 cites W2171722798 @default.
• W2276536049 cites W2322331171 @default.
• W2276536049 cites W2429744838 @default.
• W2276536049 cites W2530014580 @default.
• W2276536049 hasPublicationYear "2014" @default.
• W2276536049 type Work @default.
• W2276536049 sameAs 2276536049 @default.
• W2276536049 citedByCount "0" @default.
• W2276536049 crossrefType "posted-content" @default.
• W2276536049 hasAuthorship W2276536049A5030636719 @default.
• W2276536049 hasAuthorship W2276536049A5083369904 @default.
• W2276536049 hasConcept C104317684 @default.
• W2276536049 hasConcept C111472728 @default.
• W2276536049 hasConcept C113968399 @default.
• W2276536049 hasConcept C121608353 @default.
• W2276536049 hasConcept C134305767 @default.
• W2276536049 hasConcept C138885662 @default.
• W2276536049 hasConcept C1491633281 @default.
• W2276536049 hasConcept C2776107976 @default.
• W2276536049 hasConcept C2779013556 @default.
• W2276536049 hasConcept C2908647359 @default.
• W2276536049 hasConcept C2983331546 @default.
• W2276536049 hasConcept C502942594 @default.
• W2276536049 hasConcept C54355233 @default.
• W2276536049 hasConcept C71924100 @default.
• W2276536049 hasConcept C86803240 @default.
• W2276536049 hasConcept C89611455 @default.
• W2276536049 hasConcept C91852762 @default.
• W2276536049 hasConcept C95444343 @default.
• W2276536049 hasConcept C96232424 @default.
• W2276536049 hasConcept C99454951 @default.
• W2276536049 hasConceptScore W2276536049C104317684 @default.
• W2276536049 hasConceptScore W2276536049C111472728 @default.
• W2276536049 hasConceptScore W2276536049C113968399 @default.
• W2276536049 hasConceptScore W2276536049C121608353 @default.
• W2276536049 hasConceptScore W2276536049C134305767 @default.
• W2276536049 hasConceptScore W2276536049C138885662 @default.
• W2276536049 hasConceptScore W2276536049C1491633281 @default.
• W2276536049 hasConceptScore W2276536049C2776107976 @default.
• W2276536049 hasConceptScore W2276536049C2779013556 @default.
• W2276536049 hasConceptScore W2276536049C2908647359 @default.
• W2276536049 hasConceptScore W2276536049C2983331546 @default.
• W2276536049 hasConceptScore W2276536049C502942594 @default.
• W2276536049 hasConceptScore W2276536049C54355233 @default.
• W2276536049 hasConceptScore W2276536049C71924100 @default.
• W2276536049 hasConceptScore W2276536049C86803240 @default.
• W2276536049 hasConceptScore W2276536049C89611455 @default.
• W2276536049 hasConceptScore W2276536049C91852762 @default.
• W2276536049 hasConceptScore W2276536049C95444343 @default.
• W2276536049 hasConceptScore W2276536049C96232424 @default.
• W2276536049 hasConceptScore W2276536049C99454951 @default.
• W2276536049 hasLocation W22765360491 @default.
• W2276536049 hasOpenAccess W2276536049 @default.
• W2276536049 hasPrimaryLocation W22765360491 @default.

• next