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- W2276673878 abstract "To date, a detailed three-dimensional (3D) analysis of cardiac shape and size has not been available. Accordingly, we developed a method for such an analysis using sectioned hearts and a computer-based 3D description of the epi- and endocardial surfaces of the left and right ventricles (LV and RV) and the interventricular septum. The accuracy of this analysis as a function of section thickness (hs) was evaluated and reference axes for the LV, RV, and myocardium determined in eight canine hearts. After diastolic arrest, the RV, LV, and their atria were fixed in formaldehyde solution at pressures of 6 and 12 cmH2O, respectively. The hearts were then cast (plastic or gelatin) and sectioned, and the surfaces were digitized. We found that 1) accurate 3D computer reconstructions and computed volumes of the LV, RV, and myocardium were obtained then hs less than or equal to 5 mm, 2) the apex-to-base circumference and cross-sectional area relations could be approximated provided hs less than 10 mm, and 3) the section centers of gravity for the LV, RV, and myocardium defined three distinct vertical lines. Thus, an accurate description of 3D configuration is obtainable by a 5-mm section thickness. The centers of gravity provide a set of geometrical references for the study of shape in normal and diseased hearts." @default.
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- W2276673878 date "1981-07-01" @default.
- W2276673878 modified "2023-10-18" @default.
- W2276673878 title "Three-dimensional myocardial and ventricular shape: a surface representation" @default.
- W2276673878 doi "https://doi.org/10.1152/ajpheart.1981.241.1.h1" @default.
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