Matches in SemOpenAlex for { <https://semopenalex.org/work/W2276707897> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2276707897 endingPage "2173" @default.
- W2276707897 startingPage "2166" @default.
- W2276707897 abstract "PURPOSE To estimate the comparative cost-effectiveness of three regimens for metastatic non-small-cell lung cancer (NSCLC). METHODS Results from a randomized clinical trial of 612 European patients with NSCLC, and cost data from an academic cancer center, the Medical College of Virginia, were analyzed. In this post-hoc economic analysis, we compared vinorelbine alone, vinorelbine plus cisplatin, and a common regimen of vindesine plus cisplatin. RESULTS Vinorelbine plus cisplatin resulted in the longest mean survival time of the three regimens, 49.6 weeks, followed by vindesine plus cisplatin, 44.3 weeks, and vinorelbine, 41.6 weeks. Compared with vinorelbine alone, vinorelbine plus cisplatin added 56 days at a cost of $2,700, resulting in a cost-effectiveness ratio of $17,700 per year of life gained. Similarly, vindesine plus cisplatin added 19 days at a cost of $1,150, or $22,100 per year of life gained. Compared with vindesine plus cisplatin, vinorelbine plus cisplatin added 37 days at a cost of $1,570, or $15,500 per year of life gained. CONCLUSION The most effective regimen of vinorelbine plus cisplatin added substantial benefit compared with vinorelbine alone or another common treatment, vindesine plus cisplatin, at a cost-effectiveness within accepted limits for medical interventions. Vindesine plus cisplatin also added benefit at an acceptable cost per year of life gained. If vinorelbine is preferred because of its toxicity profile, the additional effectiveness of cisplatin added substantial benefit at an acceptable cost. Compared with other common medical interventions, chemotherapy for NSCLC has acceptable efficacy and cost-effectiveness and should not be arbitrarily denied based on clinical or economic grounds." @default.
- W2276707897 created "2016-06-24" @default.
- W2276707897 creator A5003643842 @default.
- W2276707897 creator A5021647733 @default.
- W2276707897 creator A5066325139 @default.
- W2276707897 creator A5078091833 @default.
- W2276707897 creator A5081792160 @default.
- W2276707897 date "1995-09-01" @default.
- W2276707897 modified "2023-09-27" @default.
- W2276707897 title "Economic evaluation of a randomized clinical trial comparing vinorelbine, vinorelbine plus cisplatin, and vindesine plus cisplatin for non-small-cell lung cancer." @default.
- W2276707897 cites W1825853213 @default.
- W2276707897 cites W1859092351 @default.
- W2276707897 cites W1887945714 @default.
- W2276707897 cites W1890059187 @default.
- W2276707897 cites W1957327392 @default.
- W2276707897 cites W1991425817 @default.
- W2276707897 cites W1995675566 @default.
- W2276707897 cites W2003562529 @default.
- W2276707897 cites W2016263166 @default.
- W2276707897 cites W2016751107 @default.
- W2276707897 cites W2030304195 @default.
- W2276707897 cites W2040033995 @default.
- W2276707897 cites W2052381075 @default.
- W2276707897 cites W2083224152 @default.
- W2276707897 cites W2120848534 @default.
- W2276707897 cites W2145610570 @default.
- W2276707897 cites W2227314491 @default.
- W2276707897 cites W2262696150 @default.
- W2276707897 cites W2291356857 @default.
- W2276707897 cites W2316010036 @default.
- W2276707897 doi "https://doi.org/10.1200/jco.1995.13.9.2166" @default.
- W2276707897 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7666075" @default.
- W2276707897 hasPublicationYear "1995" @default.
- W2276707897 type Work @default.
- W2276707897 sameAs 2276707897 @default.
- W2276707897 citedByCount "82" @default.
- W2276707897 countsByYear W22767078972012 @default.
- W2276707897 countsByYear W22767078972014 @default.
- W2276707897 crossrefType "journal-article" @default.
- W2276707897 hasAuthorship W2276707897A5003643842 @default.
- W2276707897 hasAuthorship W2276707897A5021647733 @default.
- W2276707897 hasAuthorship W2276707897A5066325139 @default.
- W2276707897 hasAuthorship W2276707897A5078091833 @default.
- W2276707897 hasAuthorship W2276707897A5081792160 @default.
- W2276707897 hasConcept C126322002 @default.
- W2276707897 hasConcept C143998085 @default.
- W2276707897 hasConcept C2776256026 @default.
- W2276707897 hasConcept C2776694085 @default.
- W2276707897 hasConcept C2776755627 @default.
- W2276707897 hasConcept C2778239845 @default.
- W2276707897 hasConcept C2779321808 @default.
- W2276707897 hasConcept C2779429289 @default.
- W2276707897 hasConcept C2780350996 @default.
- W2276707897 hasConcept C2781413609 @default.
- W2276707897 hasConcept C71924100 @default.
- W2276707897 hasConceptScore W2276707897C126322002 @default.
- W2276707897 hasConceptScore W2276707897C143998085 @default.
- W2276707897 hasConceptScore W2276707897C2776256026 @default.
- W2276707897 hasConceptScore W2276707897C2776694085 @default.
- W2276707897 hasConceptScore W2276707897C2776755627 @default.
- W2276707897 hasConceptScore W2276707897C2778239845 @default.
- W2276707897 hasConceptScore W2276707897C2779321808 @default.
- W2276707897 hasConceptScore W2276707897C2779429289 @default.
- W2276707897 hasConceptScore W2276707897C2780350996 @default.
- W2276707897 hasConceptScore W2276707897C2781413609 @default.
- W2276707897 hasConceptScore W2276707897C71924100 @default.
- W2276707897 hasIssue "9" @default.
- W2276707897 hasLocation W22767078971 @default.
- W2276707897 hasLocation W22767078972 @default.
- W2276707897 hasOpenAccess W2276707897 @default.
- W2276707897 hasPrimaryLocation W22767078971 @default.
- W2276707897 hasRelatedWork W2056002207 @default.
- W2276707897 hasRelatedWork W2085142786 @default.
- W2276707897 hasRelatedWork W2170498496 @default.
- W2276707897 hasRelatedWork W2288689888 @default.
- W2276707897 hasRelatedWork W2367461116 @default.
- W2276707897 hasRelatedWork W2377331194 @default.
- W2276707897 hasRelatedWork W2381460883 @default.
- W2276707897 hasRelatedWork W2381673287 @default.
- W2276707897 hasRelatedWork W2409750682 @default.
- W2276707897 hasRelatedWork W3151628666 @default.
- W2276707897 hasVolume "13" @default.
- W2276707897 isParatext "false" @default.
- W2276707897 isRetracted "false" @default.
- W2276707897 magId "2276707897" @default.
- W2276707897 workType "article" @default.