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• W2276756486 startingPage "423" @default.
• W2276756486 abstract "Phenotypic traits, such as red hair and freckling, increase melanoma risk by 2- to 3-fold. In addition, approximately 10% of melanomas are caused by inherited germline mutations that increase melanoma risk from 4- to >1000-fold. This review highlights the key genes responsible for inherited melanoma, with an emphasis on when a patient should undergo genetic testing. Many genetic syndromes associated with increased melanoma risk are also associated with an increased risk of other cancers. Identification of these high-risk patients is essential for preventive behavior reinforcement, genetic counseling, and ensuring other required cancer screenings." @default.
• W2276756486 created "2016-06-24" @default.
• W2276756486 creator A5006117818 @default.
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• W2276756486 creator A5060993422 @default.
• W2276756486 date "2016-03-01" @default.
• W2276756486 modified "2023-10-02" @default.
• W2276756486 title "Familial skin cancer syndromes" @default.
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• W2276756486 doi "https://doi.org/10.1016/j.jaad.2015.09.070" @default.
• W2276756486 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26892652" @default.
• W2276756486 hasPublicationYear "2016" @default.
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