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- W2277203498 abstract "The hallmarks of hyperthermia and its pleotropic effects are in favour of its combined use with chemotherapy and/or radiotherapy.. Preclinical research reveals that for heat killing and synergistic effects the thermal dose is most critical. Thermal enhancement of drug cytotoxicity is accompanied by cellular death and necrosis without increasing its oncogenic potential. The induction of genetically defined stress responses can deliver danger signals to activate the host’s immune system.KeywordsSynergistic EffectDrug CytotoxicityTumour RegionSystemic ToxicitySpecialized CentreThese keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves." @default.
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- W2277203498 date "2009-01-01" @default.
- W2277203498 modified "2023-09-25" @default.
- W2277203498 title "The Heat Is on in Cancer" @default.
- W2277203498 doi "https://doi.org/10.1007/978-3-642-03895-2_65" @default.
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