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- W2277237449 abstract "Compared to non-clinical subjects, people with psychosis show poor cognitive insight as reflected in low Self-Reflectiveness and high Self-Certainty. Neuroimaging studies have reported that 1) low Self-Reflectiveness is associated with volumetric reductions in ventrolateral prefrontal cortex (VLPFC), 2) higher Self-Certainty is associated with volumetric reductions in hippocampus, and 3) higher Self-Certainty is associated with fractional anisotropy in the fornix, in people with psychosis. The aims of the current study were to expand on this research by 1) performing an exploratory whole-brain cortical thickness analysis of the neural correlates of cognitive insight, to reveal whether regions outside the VLPFC are important for cognitive insight, and 2) to evaluate associations between cognitive insight and subfields of the hippocampus, which are distinct, interacting, and have different functions. We also aimed to replicate previous research documenting associations between cognitive insight and 3) total hippocampal volumes and 4) fornix fractional anisotropy. Fifteen people with a first-episode psychosis completed the Beck Cognitive Insight Scale and provided magnetic resonance and diffusion tensor imaging scans. Cortical thickness and hippocampal volumes were analyzed in FreeSurfer, and fornixfractional anisotropy was analyzed in Diffusion Toolkit/TrackVis. Higher Self-Reflectiveness and lower Self-Certainty significantly associated with thickness and thinness in VLPFC, respectively, as well as thickness and thinness in widespread frontal, parietal and temporal cortices. No associations emerged between Self-Reflectiveness or Self-Certainty and hippocampal total or sub-field volumes, or fornix fractional anisotropy. Results suggest that the neural correlates of cognitive insight involve a network of frontal, temporal and parietal brain regions." @default.
- W2277237449 created "2016-06-24" @default.
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- W2277237449 date "2016-04-01" @default.
- W2277237449 modified "2023-10-16" @default.
- W2277237449 title "Cognitive insight is associated with cortical thickness in first-episode psychosis" @default.
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- W2277237449 cites W1965252321 @default.
- W2277237449 cites W1965907779 @default.
- W2277237449 cites W1966752480 @default.
- W2277237449 cites W1971120154 @default.
- W2277237449 cites W1973127790 @default.
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- W2277237449 cites W1998454877 @default.
- W2277237449 cites W2001469430 @default.
- W2277237449 cites W2001497417 @default.
- W2277237449 cites W2004293194 @default.
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- W2277237449 cites W2019091904 @default.
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- W2277237449 doi "https://doi.org/10.1016/j.schres.2016.02.026" @default.
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