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• W2277393968 abstract "Abstract Objectives To compare clinical outcomes and costs between two administration strategies of omalizumab treatment. Method We evaluated two cohorts of patients with uncontrolled severe asthma over a 1-year period. Patients received the treatment in the primary care center in Hospital A and conventional hospital administration in Hospital B. Results We studied 130 patients, 86 in Hospital A and 44 in Hospital B, 30 men (24%) and 100 women (76%), age 50±15 years, FEV1% 67±22%, body mass index (BMI) 28±6 kg/m2, 639±747 UI IgE/mL, followed for 24±11 months (12–45), Asthma Control Test (ACT) score 12±4 and Asthma Control Questionnaire (ACQ) 3±2. There were no significant pretreatment differences between the groups in hospital admissions and emergency room visits in the previous year, nor in proportion of patients receiving oral steroids. Evaluations were performed at baseline and after 12 months of treatment, revealing significant differences in ACT (P Conclusion The administration of omalizumab in ambulatory health centers achieved the same clinical results as a hospital administration strategy, but with lower costs." @default.
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• W2277393968 date "2016-04-01" @default.
• W2277393968 modified "2023-09-27" @default.
• W2277393968 title "Comparison of Costs and Clinical Outcomes Between Hospital and Outpatient Administration of Omalizumab in Patients With Severe Uncontrolled Asthma" @default.
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• W2277393968 doi "https://doi.org/10.1016/j.arbr.2016.02.011" @default.
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