Matches in SemOpenAlex for { <https://semopenalex.org/work/W2277456241> ?p ?o ?g. }
Showing items 1 to 73 of
73
with 100 items per page.
- W2277456241 endingPage "51" @default.
- W2277456241 startingPage "348" @default.
- W2277456241 abstract "This study was purposed to analyze the clinical features and evaluate the efficacy of thalidomide combined with VAD regimen for treatment of osteosclerotic myeloma (POEMS syndrome). The data of 27 patients with POEMS syndrome in the First Affiliated Hospital of Zhengzhou University were analyzed retrospectively, including clinical manifestations, laboratory tests, treatments and prognosis. The results showed that the polyneuropathy was observed in 27 patients (27/27), hepato-spleno-lymphadenectasis was found in 15 patients (15/27), endocrinopathy was found in 24 patients (24/27), skin changes was observed in 22 patients (22/27). M protein was found in 23 patients (23/27); in addition to these clinical manifestations, the papilledema serous cavity effusion and sclerotic bone lesion were also frequently observed in patients with POEMS syndrome. The remission rates of treatment of POEMS syndrome with thalidomide combined with VAD regimen for organomegaly, edema, skin changes, and endocrinopathy were 60, 58.3, 41 and 45.8 respectively. The level of serum M protein and the nervous system ODSS value decreased greatly after treatment (P < 0.01). It is concluded that the clinical characteristics of POEMS syndrome are complicated and easy to be misdiagnosed, and the evidence of monoclonal plasma cell hyperplasia should be actively searched for those patients whose serum M protein is negative. Thalidomide combined with VAD regimen for treatment of patients with POEMS syndrome has advantages such as significant curative effects, less side-effects, good tolerance, and higher safety and can be chosen as a preferred approach." @default.
- W2277456241 created "2016-06-24" @default.
- W2277456241 creator A5005371991 @default.
- W2277456241 creator A5009440660 @default.
- W2277456241 creator A5010762548 @default.
- W2277456241 creator A5031753071 @default.
- W2277456241 creator A5038054864 @default.
- W2277456241 creator A5038623685 @default.
- W2277456241 creator A5065919199 @default.
- W2277456241 date "2012-04-01" @default.
- W2277456241 modified "2023-09-24" @default.
- W2277456241 title "[Clinical observation of thalidomide combined with VAD regimen for treatment of osteosclerotic myeloma (POEMS syndrome)]." @default.
- W2277456241 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22541096" @default.
- W2277456241 hasPublicationYear "2012" @default.
- W2277456241 type Work @default.
- W2277456241 sameAs 2277456241 @default.
- W2277456241 citedByCount "1" @default.
- W2277456241 countsByYear W22774562412017 @default.
- W2277456241 crossrefType "journal-article" @default.
- W2277456241 hasAuthorship W2277456241A5005371991 @default.
- W2277456241 hasAuthorship W2277456241A5009440660 @default.
- W2277456241 hasAuthorship W2277456241A5010762548 @default.
- W2277456241 hasAuthorship W2277456241A5031753071 @default.
- W2277456241 hasAuthorship W2277456241A5038054864 @default.
- W2277456241 hasAuthorship W2277456241A5038623685 @default.
- W2277456241 hasAuthorship W2277456241A5065919199 @default.
- W2277456241 hasConcept C126322002 @default.
- W2277456241 hasConcept C141071460 @default.
- W2277456241 hasConcept C188758523 @default.
- W2277456241 hasConcept C2775876775 @default.
- W2277456241 hasConcept C2775892965 @default.
- W2277456241 hasConcept C2776210965 @default.
- W2277456241 hasConcept C2776364478 @default.
- W2277456241 hasConcept C2776367607 @default.
- W2277456241 hasConcept C2778551932 @default.
- W2277456241 hasConcept C2779609412 @default.
- W2277456241 hasConcept C2781413609 @default.
- W2277456241 hasConcept C71924100 @default.
- W2277456241 hasConcept C90924648 @default.
- W2277456241 hasConceptScore W2277456241C126322002 @default.
- W2277456241 hasConceptScore W2277456241C141071460 @default.
- W2277456241 hasConceptScore W2277456241C188758523 @default.
- W2277456241 hasConceptScore W2277456241C2775876775 @default.
- W2277456241 hasConceptScore W2277456241C2775892965 @default.
- W2277456241 hasConceptScore W2277456241C2776210965 @default.
- W2277456241 hasConceptScore W2277456241C2776364478 @default.
- W2277456241 hasConceptScore W2277456241C2776367607 @default.
- W2277456241 hasConceptScore W2277456241C2778551932 @default.
- W2277456241 hasConceptScore W2277456241C2779609412 @default.
- W2277456241 hasConceptScore W2277456241C2781413609 @default.
- W2277456241 hasConceptScore W2277456241C71924100 @default.
- W2277456241 hasConceptScore W2277456241C90924648 @default.
- W2277456241 hasIssue "2" @default.
- W2277456241 hasLocation W22774562411 @default.
- W2277456241 hasOpenAccess W2277456241 @default.
- W2277456241 hasPrimaryLocation W22774562411 @default.
- W2277456241 hasRelatedWork W1679609229 @default.
- W2277456241 hasRelatedWork W1850806629 @default.
- W2277456241 hasRelatedWork W2007026202 @default.
- W2277456241 hasRelatedWork W2092211814 @default.
- W2277456241 hasRelatedWork W2102823161 @default.
- W2277456241 hasRelatedWork W2277456241 @default.
- W2277456241 hasRelatedWork W2396173062 @default.
- W2277456241 hasRelatedWork W2994735639 @default.
- W2277456241 hasRelatedWork W2999006280 @default.
- W2277456241 hasRelatedWork W3159534282 @default.
- W2277456241 hasVolume "20" @default.
- W2277456241 isParatext "false" @default.
- W2277456241 isRetracted "false" @default.
- W2277456241 magId "2277456241" @default.
- W2277456241 workType "article" @default.