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- W2277869830 abstract "Brain hemorrhage is a feared complication of immediate anticoagulation of cardiogenic brain embolism. The clinical features of 62 patients with CT evidence of brain hemorrhage complicating embolic stroke were studied. Worsening with hemmorhagic transformation occurred in 15 anticoagulated and two non-anticoagulated patients, with no apparent relationship with patient age or embolic source. Of anticoagulated (AC) patients who worsened, 7 were hypertensive, 11 were excessively anticoagulated and 9 had large infarcts. There were 3 AC patients who worsened who were neither hypertensive, nor excessively anticoagulated. Asymptomatic hemorrhagic transformation was more common than hemorrhagic worsening, occurring in 45 patients. Factors associated with hemorrhage and worsening include large infarct size (60 % vs 21 %) and initiation of AC after early (less than 12 hrs from stroke onset) CT (62 % vs 37 %). The occurrence of symptomatic brain hemorrhage in embolic stroke is not entirely predicable. In patients with large embolic strokes, postponing anticoagulation for several days may be prudent." @default.
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- W2277869830 date "1986-01-01" @default.
- W2277869830 modified "2023-09-27" @default.
- W2277869830 title "Brain Hemorrhage in Embolic Stroke" @default.
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- W2277869830 doi "https://doi.org/10.1007/978-1-4613-2327-3_24" @default.
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