Matches in SemOpenAlex for { <https://semopenalex.org/work/W2277886068> ?p ?o ?g. }
Showing items 1 to 74 of
74
with 100 items per page.
- W2277886068 endingPage "300" @default.
- W2277886068 startingPage "295" @default.
- W2277886068 abstract "The reaction between aflatoxin B1 and sodium bisulfite yielded almost quantitatively a light yellow, highly fluorescent water-soluble product, aflatoxin B1S. Reverse-phase (C18) high pressure liquid chromatography (with and without the paired-ion technique), and normal- and reverse-phase thin layer chromatography revealed the ionic product at greater than 98% yield. The product's intense fluorescence, identical in color to that of aflatoxins B1 and B2, supported the conclusion that the lactone of aflatoxin B1 was not opened by bisulfite and that the reaction took place at some other location on the aflatoxin B1 molecule. The UV spectrum of aflatoxin B1S exhibited identical absorbance maxima to aflatoxin B1 and these maxima exhibited no bathochromic shift in alkaline solution. Aflatoxin B1S exhibited change to bright yellow fluorescence under 365 nm UV light after being sprayed with 20% sulfuric acid in methanol. The IR spectrum of aflatoxin B1S indicated the vinylene group of the furofuran ring system of aflatoxin B1 was missing from aflatoxin B1S, whereas the coumarin-cyclopentenone ring system present in aflatoxin B1 was intact in aflatoxin B1S. Furthermore, the IR spectrum suggested the presence of a sulfonate moiety in B1S. Proton NMR spectra of aflatoxin B1S also indicated that the cyclopentenone region was intact and that the furofuran had undergone reaction with bisulfite. Integration of the NMR spectrum of aflatoxin B1S revealed 12.75 to 13.25 protons, consistent with a bisulfite addition across the double bond of aflatoxin B1 to form aflatoxin B1S. Aflatoxins B2 and G2 were not susceptible to the action of bisulfite, again supporting the conclusion that bisulfite acts at the unsaturation in the furofuran ring system of aflatoxin B1. There was no evidence that aflatoxin B2 was produced in the degradation of aflatoxin B1 by bisulfite under these conditions. The fact that previously reported chemical modifications of this furofuran ring system resulted in reduced toxicity support the potential utility of bisulfite as a means of detoxification of aflatoxin-contaminated commodities." @default.
- W2277886068 created "2016-06-24" @default.
- W2277886068 creator A5003468301 @default.
- W2277886068 creator A5009971731 @default.
- W2277886068 creator A5016720458 @default.
- W2277886068 date "1983-04-01" @default.
- W2277886068 modified "2023-10-03" @default.
- W2277886068 title "Destruction of Aflatoxin B1 with Sodium Bisulfite: Isolation of the Major Product Aflatoxin B1S" @default.
- W2277886068 doi "https://doi.org/10.4315/0362-028x-46.4.295" @default.
- W2277886068 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30913587" @default.
- W2277886068 hasPublicationYear "1983" @default.
- W2277886068 type Work @default.
- W2277886068 sameAs 2277886068 @default.
- W2277886068 citedByCount "22" @default.
- W2277886068 countsByYear W22778860682012 @default.
- W2277886068 countsByYear W22778860682013 @default.
- W2277886068 countsByYear W22778860682014 @default.
- W2277886068 countsByYear W22778860682017 @default.
- W2277886068 countsByYear W22778860682018 @default.
- W2277886068 countsByYear W22778860682021 @default.
- W2277886068 countsByYear W22778860682022 @default.
- W2277886068 crossrefType "journal-article" @default.
- W2277886068 hasAuthorship W2277886068A5003468301 @default.
- W2277886068 hasAuthorship W2277886068A5009971731 @default.
- W2277886068 hasAuthorship W2277886068A5016720458 @default.
- W2277886068 hasBestOaLocation W22778860681 @default.
- W2277886068 hasConcept C104317684 @default.
- W2277886068 hasConcept C150194340 @default.
- W2277886068 hasConcept C178790620 @default.
- W2277886068 hasConcept C185592680 @default.
- W2277886068 hasConcept C190727270 @default.
- W2277886068 hasConcept C2775959488 @default.
- W2277886068 hasConcept C2775959680 @default.
- W2277886068 hasConcept C2777292910 @default.
- W2277886068 hasConcept C2777903533 @default.
- W2277886068 hasConcept C31903555 @default.
- W2277886068 hasConcept C40758303 @default.
- W2277886068 hasConcept C43617362 @default.
- W2277886068 hasConcept C55493867 @default.
- W2277886068 hasConceptScore W2277886068C104317684 @default.
- W2277886068 hasConceptScore W2277886068C150194340 @default.
- W2277886068 hasConceptScore W2277886068C178790620 @default.
- W2277886068 hasConceptScore W2277886068C185592680 @default.
- W2277886068 hasConceptScore W2277886068C190727270 @default.
- W2277886068 hasConceptScore W2277886068C2775959488 @default.
- W2277886068 hasConceptScore W2277886068C2775959680 @default.
- W2277886068 hasConceptScore W2277886068C2777292910 @default.
- W2277886068 hasConceptScore W2277886068C2777903533 @default.
- W2277886068 hasConceptScore W2277886068C31903555 @default.
- W2277886068 hasConceptScore W2277886068C40758303 @default.
- W2277886068 hasConceptScore W2277886068C43617362 @default.
- W2277886068 hasConceptScore W2277886068C55493867 @default.
- W2277886068 hasIssue "4" @default.
- W2277886068 hasLocation W22778860681 @default.
- W2277886068 hasLocation W22778860682 @default.
- W2277886068 hasOpenAccess W2277886068 @default.
- W2277886068 hasPrimaryLocation W22778860681 @default.
- W2277886068 hasRelatedWork W1604346844 @default.
- W2277886068 hasRelatedWork W1986731011 @default.
- W2277886068 hasRelatedWork W2025761168 @default.
- W2277886068 hasRelatedWork W2049975504 @default.
- W2277886068 hasRelatedWork W2137830436 @default.
- W2277886068 hasRelatedWork W2274232696 @default.
- W2277886068 hasRelatedWork W2277886068 @default.
- W2277886068 hasRelatedWork W2286141684 @default.
- W2277886068 hasRelatedWork W2314416299 @default.
- W2277886068 hasRelatedWork W268638004 @default.
- W2277886068 hasVolume "46" @default.
- W2277886068 isParatext "false" @default.
- W2277886068 isRetracted "false" @default.
- W2277886068 magId "2277886068" @default.
- W2277886068 workType "article" @default.