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- W2277889670 abstract "Hepatic adenomas are uncommon epithelial tumours. They usually appear in women between 20 and 44 years old. They are commonly located in the right hepatic lobe and are typically solitary masses. Multiple adenomas can present in patients with prolonged use of oral contraceptive pills, glycogen storage diseases and hepatic adenomatosis. A 35 year-old woman without any significant past medical history, with a chief complaint that started in December 2012 with oppressive, mild intensity abdominal pain located in right upper quadrant in the abdomen on deep palpation. With an abdominal ultrasound showing a mass of 91 cm × 82 cm × 65 cm located in the right flank, isoechogenic with internal vascularity. Contrast computed tomography scan showing an ovoid tumour with circumscribed borders, with heterogenic intense reinforcement and displacement of adjacent structures with dimensions of 88 cm × 71 cm × 80 cm. In laparotomy, excision of the tumour and cholecystectomy with the trans surgical findings of an 8 cm tumour with a pedicle containing one artery and one vein coming from the hepatic free border with strong adhesions to the gallbladder. Pathologic diagnosis: extracapsular hepatic adenoma. Incidence of hepatic adenomas has increased in the last decades, in a parallel fashion with the introduction of oral contraceptive pills, showing association with glycogen storage diseases and to a lesser degree with diabetes and pregnancy. Diagnosis is clinical with the aid of imaging studies. Prognosis of hepatic adenomas is not well established, therefore, management depends on symptoms, size, number, location and certainty of diagnosis. Los adenomas hepáticos son tumores epiteliales poco comunes. Usualmente aparecen en mujeres de 20 a 44 años; con frecuencia están localizados en el lóbulo hepático derecho y son típicamente solitarios. Los adenomas múltiples suelen presentarse en pacientes con uso prolongado de anticonceptivos orales, enfermedades de almacenamiento de glucógeno y adenomatosis hepática. Paciente femenina de 35 años sin antecedentes de importancia. Inició el padecimiento motivo de consulta en diciembre del 2012, con dolor abdominal opresivo de mediana intensidad en hipocondrio derecho. A la exploración de abdomen, se observa tumoración abdominal en flanco derecho y dolor a palpación profunda. El ultrasonido abdominal con tumoración de 91 × 82 × 65 cm localizada en flanco derecho, isoecoica con vascularidad interna. La tomografía axial computada contrastada abdominal muestra tumor ovoide de bordes delimitados, y reforzamiento intenso heterogéneo que desplaza estructuras adyacentes, con diámetros de 88 × 71 × 80 cm. Se realizó laparotomía con exéresis de tumor y colecistectomía con hallazgos transquirúrgicos: tumor de 8 cm de diámetro, con pedículo que incluye vena y arteria nutricia proveniente de borde hepático, adherido a vesícula biliar. Diagnóstico histopatológico de adenoma hepático extracapsular. La incidencia de los adenomas hepáticos se ha incrementado en las últimas décadas, de forma casi paralela a la introducción de los anticonceptivos orales, además de asociarse con enfermedades de almacenamiento de colágeno y, de forma menos común, con diabetes mellitus y embarazo. El diagnóstico es clínico con ayuda de estudios de imagen. El pronóstico de los adenomas hepáticos no está bien establecido. El tratamiento se establece de acuerdo con los síntomas, tamaño, número, localización y la certeza en el diagnóstico." @default.
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- W2277889670 date "2017-03-01" @default.
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- W2277889670 title "Extracapsular hepatic adenoma. Case report and literature review" @default.
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- W2277889670 doi "https://doi.org/10.1016/j.circen.2017.02.005" @default.
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