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- W2278204920 abstract "Acute respiratory distress syndrome (ARDS) is a major cause of morbidity and mortality in critically ill patients occurring in the context of sepsis and other systemic inflammatory disorders. Health disparities correlated with socioeconomic status and health care access disproportionately affect racial and ethnic minorities and lead to differences in prevalence and outcomes of ARDS. In addition, the role of genetic and environmental factors in critical illness outcomes has been examined. Multiple studies have highlighted differences in allelic variant frequencies between European descendant and African descent individuals. These allelic variants play an important role in inflammatory and infectious pathways in conditions that predispose to ARDS. In this chapter, we address race and ethnicity in the context of the complex genetic and environmental interactions that influence disparities in outcomes in ARDS in African American and Hispanic/Latino populations, groups most affected by health care disparities. We postulate that multiple factors contribute to poor outcomes in ethnic and racial minorities with ARDS and that precision medicine can be a realistic approach to overcome those disparities." @default.
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- W2278204920 date "2016-01-01" @default.
- W2278204920 modified "2023-09-27" @default.
- W2278204920 title "Health Disparities in ARDS" @default.
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- W2278204920 doi "https://doi.org/10.1007/978-3-319-23675-9_7" @default.
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