Matches in SemOpenAlex for { <https://semopenalex.org/work/W2278659539> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W2278659539 endingPage "1057" @default.
- W2278659539 startingPage "1052" @default.
- W2278659539 abstract "BACKGROUND Previous studies have demonstrated the importance of bone marrow (BM) harvest yield in determining transplant outcomes, but little is known regarding donor and procedure variables associated with achievement of an optimal yield. We hypothesized that donor demographics and variables relating to the procedure were likely to impact the yield (total nucleated cells [TNCs]/kg recipient weight) and quality (TNCs/mL) of the harvest. STUDY DESIGN AND METHODS To test our hypothesis, BM harvests of 110 consecutive unrelated donors were evaluated. The relationship between donor or procedure characteristics and the BM harvest yield was examined. RESULTS The relationship between donor and recipient weight significantly influenced the harvest yield; only 14% of BM harvests from donors who weighed less than their recipient achieved a TNC count of more than 4 × 10 8 /kg compared to 56% of harvests from donors heavier than their recipient (p = 0.001). Higher‐volume harvests were significantly less likely to achieve an optimal yield than lower‐volume harvests (32% vs. 78%; p = 0.007), and higher‐volume harvests contained significantly fewer TNCs/mL, indicating peripheral blood contamination. BM harvest quality also varied significantly between collection centers adding to recent concerns regarding maintenance of BM harvest expertise within the transplant community. CONCLUSION Since the relationship between donor and recipient weight has a critical influence yield, we recommend prioritizing this secondary donor characteristic when selecting from multiple well‐matched donors. Given the declining number of requests for BM harvests, it is crucial that systems are developed to train operators and ensure expertise in this procedure is retained." @default.
- W2278659539 created "2016-06-24" @default.
- W2278659539 creator A5020482451 @default.
- W2278659539 creator A5020505976 @default.
- W2278659539 creator A5026562569 @default.
- W2278659539 creator A5032478325 @default.
- W2278659539 creator A5039305143 @default.
- W2278659539 creator A5067928308 @default.
- W2278659539 date "2016-02-21" @default.
- W2278659539 modified "2023-09-23" @default.
- W2278659539 title "Harvests from bone marrow donors who weigh less than their recipients are associated with a significantly increased probability of a suboptimal harvest yield" @default.
- W2278659539 cites W1934677454 @default.
- W2278659539 cites W1958839778 @default.
- W2278659539 cites W1969005669 @default.
- W2278659539 cites W1977694249 @default.
- W2278659539 cites W1983821870 @default.
- W2278659539 cites W1999056980 @default.
- W2278659539 cites W2010524169 @default.
- W2278659539 cites W2017926367 @default.
- W2278659539 cites W2021121601 @default.
- W2278659539 cites W2045097974 @default.
- W2278659539 cites W2049593092 @default.
- W2278659539 cites W2050654657 @default.
- W2278659539 cites W2061718990 @default.
- W2278659539 cites W2071411325 @default.
- W2278659539 cites W2074942153 @default.
- W2278659539 cites W2115228468 @default.
- W2278659539 cites W2126021331 @default.
- W2278659539 cites W2149502955 @default.
- W2278659539 cites W2157405305 @default.
- W2278659539 cites W2158188228 @default.
- W2278659539 cites W2159601755 @default.
- W2278659539 cites W2163682534 @default.
- W2278659539 cites W2327202480 @default.
- W2278659539 cites W2409904921 @default.
- W2278659539 cites W58931608 @default.
- W2278659539 doi "https://doi.org/10.1111/trf.13509" @default.
- W2278659539 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/26898844" @default.
- W2278659539 hasPublicationYear "2016" @default.
- W2278659539 type Work @default.
- W2278659539 sameAs 2278659539 @default.
- W2278659539 citedByCount "14" @default.
- W2278659539 countsByYear W22786595392016 @default.
- W2278659539 countsByYear W22786595392017 @default.
- W2278659539 countsByYear W22786595392018 @default.
- W2278659539 countsByYear W22786595392019 @default.
- W2278659539 countsByYear W22786595392020 @default.
- W2278659539 countsByYear W22786595392021 @default.
- W2278659539 countsByYear W22786595392023 @default.
- W2278659539 crossrefType "journal-article" @default.
- W2278659539 hasAuthorship W2278659539A5020482451 @default.
- W2278659539 hasAuthorship W2278659539A5020505976 @default.
- W2278659539 hasAuthorship W2278659539A5026562569 @default.
- W2278659539 hasAuthorship W2278659539A5032478325 @default.
- W2278659539 hasAuthorship W2278659539A5039305143 @default.
- W2278659539 hasAuthorship W2278659539A5067928308 @default.
- W2278659539 hasConcept C126322002 @default.
- W2278659539 hasConcept C134121241 @default.
- W2278659539 hasConcept C141071460 @default.
- W2278659539 hasConcept C144024400 @default.
- W2278659539 hasConcept C149923435 @default.
- W2278659539 hasConcept C191897082 @default.
- W2278659539 hasConcept C192562407 @default.
- W2278659539 hasConcept C2780007613 @default.
- W2278659539 hasConcept C2780084366 @default.
- W2278659539 hasConcept C71924100 @default.
- W2278659539 hasConceptScore W2278659539C126322002 @default.
- W2278659539 hasConceptScore W2278659539C134121241 @default.
- W2278659539 hasConceptScore W2278659539C141071460 @default.
- W2278659539 hasConceptScore W2278659539C144024400 @default.
- W2278659539 hasConceptScore W2278659539C149923435 @default.
- W2278659539 hasConceptScore W2278659539C191897082 @default.
- W2278659539 hasConceptScore W2278659539C192562407 @default.
- W2278659539 hasConceptScore W2278659539C2780007613 @default.
- W2278659539 hasConceptScore W2278659539C2780084366 @default.
- W2278659539 hasConceptScore W2278659539C71924100 @default.
- W2278659539 hasIssue "5" @default.
- W2278659539 hasLocation W22786595391 @default.
- W2278659539 hasLocation W22786595392 @default.
- W2278659539 hasOpenAccess W2278659539 @default.
- W2278659539 hasPrimaryLocation W22786595391 @default.
- W2278659539 hasRelatedWork W1586374228 @default.
- W2278659539 hasRelatedWork W2003938723 @default.
- W2278659539 hasRelatedWork W2045240138 @default.
- W2278659539 hasRelatedWork W2047967234 @default.
- W2278659539 hasRelatedWork W2118496982 @default.
- W2278659539 hasRelatedWork W2364998975 @default.
- W2278659539 hasRelatedWork W2369162477 @default.
- W2278659539 hasRelatedWork W2439875401 @default.
- W2278659539 hasRelatedWork W4238867864 @default.
- W2278659539 hasRelatedWork W2525756941 @default.
- W2278659539 hasVolume "56" @default.
- W2278659539 isParatext "false" @default.
- W2278659539 isRetracted "false" @default.
- W2278659539 magId "2278659539" @default.
- W2278659539 workType "article" @default.